[1]naphthylmethylene-malonic acid | 58818-75-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: [1]naphthylmethylene-malonic acid
• 英文别名: [1]Naphthylmethylen-malonsaeure；[(Naphthalen-1-yl)methylidene]propanedioic acid；2-(naphthalen-1-ylmethylidene)propanedioic acid
• CAS: 58818-75-0
• 化学式: C₁₄H₁₀O₄
• 分子量: 242.231
• InChiKey: FUMCVFJTULMDNL-UHFFFAOYSA-N

物化性质

• 熔点：
  214-215 °C
• 沸点：
  481.6±33.0 °C(Predicted)
• 密度：
  1.424±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  [1]naphthylmethylene-malonic acid 在 三氯化铝 、 氯化亚砜 作用下， 生成 1-oxo-1H-phenalene-2-carboxylic acid
  参考文献：
  名称：

  p-quinone methides as geometric analogues of quinolone carboxylate antibacterials

  摘要：

  In an attempt to examine the role of the N(I)-alkyl or -aryl moiety of the quinolone antibacterials, several quinone methides such as perinaphthindenone carboxylates (6) were synthesized as 1-carba(sp(2)) analogues of the quinolone structure, and found to have no antibacterial activity. These results together with literature information are interpreted as the necessity of a: least one nitrogen atom at the position of 1, 3, 4a, 6 or 8 in the quinolone-like skeleton for the antibacterial activities. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/0960-894x(96)00218-1
• 作为产物：
  描述：

  丙二酸 、 1-萘甲醛 在 bentonite 作用下， 反应 0.08h， 以94%的产率得到[1]naphthylmethylene-malonic acid
  参考文献：
  名称：

  Solvent-free bentonite-catalyzed condensation of malonic acid and aromatic aldehydes under microwave irradiation

  摘要：

  研究了在膨润土存在下，丙二酸与芳香醛之间的无溶剂缩合反应。在微波辐射条件下，通过非常短的反应时间制备出了各种二酸，产率从中等到良好不等。

  DOI：

  10.1039/b009803p

文献信息

• Neutral metalloendopeptidase inhibitors in the treatment of hypertension
  申请人：SCHERING CORPORATION

  公开号：EP0254032A2

  公开（公告）日：1988-01-27

  The method of treating hypertension with neutral metalloendopeptidase (NMEP) inhibitors, NMEP inhibitors in combination with atrial peptides, and NMEP inhibitors in combination with angiotensin converting enzyme inhibitors, as well as pharmaceutical compositions therefor, are disclosed.

  本研究公开了使用中性金属内肽酶（NMEP）抑制剂、NMEP 抑制剂与心房肽联合使用、NMEP 抑制剂与血管紧张素转换酶抑制剂联合使用治疗高血压的方法及其药物组合物。
• METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR USE IN POLYMERIZATION OF OLEFIN, CATALYST FOR USE IN POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER
  申请人：Toho Titanium CO., LTD.

  公开号：EP2876118A1

  公开（公告）日：2015-05-27

  A method for producing a solid catalyst component for olefin polymerization produces a novel solid catalyst component for olefin polymerization that achieves excellent olefin polymerization activity and activity with respect to hydrogen during polymerization, and can produce an olefin polymer that exhibits a high MFR, high stereoregularity, and excellent rigidity. The method includes a first step that brings a magnesium compound, a tetravalent titanium halide compound, and one or more first internal electron donor compounds selected from specific aromatic dicarboxylic diesters into contact with each other to effect a reaction, followed by washing, a second step that brings a tetravalent titanium halide compound and one or more second internal electron donor compounds into contact with a product obtained by the first step to effect a reaction, followed by washing, and a third step that brings one or more third internal electron donor compounds into contact with a product obtained by the second step to effect a reaction.

  一种生产烯烃聚合用固体催化剂组分的方法可生产出一种新型的烯烃聚合用固体催化剂组分，该组分具有优异的烯烃聚合活性和聚合过程中对氢的活性，并可生产出具有高MFR、高立体规整度和优异刚性的烯烃聚合物。该方法包括第一步，使镁化合物、四价卤化钛化合物和一种或多种选自特定芳香族二羧酸二酯的第一内部电子供体化合物相互接触以发生反应，然后进行洗涤、第二步：使四价卤化钛化合物和一种或多种第二内部电子供体化合物与第一步得到的产物接触，以发生反应，然后进行洗涤；第三步：使一种或多种第三内部电子供体化合物与第二步得到的产物接触，以发生反应。
• PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, CATALYST FOR POLYMERIZING OLEFINS, AND PRODUCTION METHOD FOR POLYMERIZED OLEFINS
  申请人：TOHO TITANIUM CO., LTD.

  公开号：EP2963063A1

  公开（公告）日：2016-01-06

  A method for producing a solid catalyst component for olefin polymerization produces a novel solid catalyst component for olefin polymerization that achieves excellent olefin polymerization activity and activity with respect to hydrogen during polymerization, and can produce an olefin polymer that exhibits a high MFR, high stereoregularity, and excellent rigidity. The method includes a first step that brings a magnesium compound, a tetravalent titanium halide compound, and one or more first internal electron donor compounds excluding an aromatic dicarboxylic acid diester into contact with each other to effect a reaction, followed by washing; a second step that brings a tetravalent titanium halide compound and one or more second internal electron donor compounds into contact with a product obtained by the first step to effect a reaction, followed by washing; and a third step that brings one or more third internal electron donor compounds into contact with a product obtained by the second step to effect a reaction.

  一种生产烯烃聚合用固体催化剂组分的方法可生产出一种新型的烯烃聚合用固体催化剂组分，该组分具有优异的烯烃聚合活性和聚合过程中对氢的活性，并可生产出具有高MFR、高立体规整度和优异刚性的烯烃聚合物。该方法包括第一步，使镁化合物、四价卤化钛化合物和一种或多种第一内部电子供体化合物（不包括芳香族二羧酸二酯）相互接触以发生反应，然后进行洗涤；第二步，使四价卤化钛化合物和一种或多种第二内部电子供体化合物与第一步得到的产物接触，以发生反应，然后进行洗涤；以及第三步，使一种或多种第三内部电子供体化合物与第二步得到的产物接触，以发生反应。
• Solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer
  申请人：TOHO TITANIUM CO., LTD.

  公开号：US11192965B2

  公开（公告）日：2021-12-07

  Provided is a solid catalyst component for olefin polymerization comprising an electron-donating compound other than a phthalate, the solid catalyst component being equal in the olefin-polymerizing activity and in the primary physical properties of the resulting polymer such as stereoregularity and molecular weight distribution to those with use of a phthalate as an electron-donating compound. A solid catalyst component for olefin polymerization comprises a magnesium atom, a titanium atom, a halogen atom, an ester compound (A) represented by a general formula (1) and a diester compound (B) represented by a general formula (2), wherein a ratio represented by the following expression: (content (mass %) of ester compound (A)/content (mass %) of diester compound (B)) is 0.05 to 50.

  本发明提供了一种用于烯烃聚合的固体催化剂组分，该组分包括邻苯二甲酸酯以外的一种电子供体化合物，该固体催化剂组分在烯烃聚合活性和所得聚合物的主要物理性质（如立体规整度和分子量分布）方面与使用邻苯二甲酸酯作为电子供体化合物的催化剂组分相同。用于烯烃聚合的固体催化剂组分包括镁原子、钛原子、卤素原子、通式（1）表示的酯化合物 （A）和通式（2）表示的二酯化合物（B），其中 由以下表达式表示的比例： (酯化合物（A）的含量（质量百分比）/二酯化合物（B）的含量（质量百分比）) 为 0.05 至 50。
• Colored wax articles
  申请人：——

  公开号：US20010051680A1

  公开（公告）日：2001-12-13

  Disclosed are improved solid, colored wax-based article having longer color shelf-life. The invention comprises a synthetic wax, a colorant, and an effective amount of a compound of the formula (1) 1 having symbols defined in the text. The preferred embodiments of the articles contain (1) that exhibits a UV absorptivity greater than or equal to 70 liters per gram-cm. at a wavelength of less than or equal to 400 nm, as measured in either methanol, toluene or chloroform, using a conventional UV spectrophotometer. The uses for the articles include candles, crayons, fertilizer coatings, rosebush coatings, plant grafting, sealants, sun-cracking protection of rubber and plastic products, paper coating, packaging food products, electrical insulation, waterproofing and cleaning compounds, carbon paper, and precision investment casting.

  本发明公开了具有更长颜色保存期的改进型固体有色蜡基制品。本发明包括合成蜡、着色剂和有效量的式 (1) 化合物 1 文中定义的符号。 本发明的优选实施例中，(1)在波长小于或等于 400 纳米的甲醇、甲苯或氯仿中，用常规紫外分光光度计测量，紫外线吸收率大于或等于 70 升/克-厘米。 这些物品的用途包括蜡烛、蜡笔、肥料涂层、玫瑰树丛涂层、植物嫁接、密封剂、橡胶和塑料产品的防晒裂保护、纸张涂层、食品包装、电绝缘、防水和清洁化合物、碳纸和精密投资铸造。