bis(3,5-diisopropylsalicylato)(1,10-phenanthroline) copper(II) | 154155-20-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: bis(3,5-diisopropylsalicylato)(1,10-phenanthroline) copper(II)
• CAS: 154155-20-1
• 化学式: C₃₈H₄₂CuN₂O₆
• 分子量: 686.307
• InChiKey: QUGCDWOMSJPIRX-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  1,10-菲罗啉 、 tetrakis(acetato)diaquadicopper(II) 、 3,5-二异丙基邻羟基苯甲酸 以 乙醇 为溶剂， 以73%的产率得到bis(3,5-diisopropylsalicylato)(1,10-phenanthroline) copper(II)
  参考文献：
  名称：

  Cytotoxicity and antiviral activity of transition-metal salicylato complexes and crystal structure of Bis(diisopropylsalicylato)(1,10-phenanthroline)copper(II)

  摘要：

  Complexes of Cu(II), Fe(III), Co(II), Ni(II), Ti(IV) and Zn(II) with 3,5-disubstituted salicylates, and ternary complexes of Cu(II) containing substituted phenanthrolines have been prepared and characterised. The crystal structure of bis(diisopropylsalicylato)(1,10-phenanthroline)copper(II), [Cu(phen)(Hdips)2], has been determined; Cu(II) is in a tetragonal co-ordination environment with in-plane bonds to 2 nitrogens from phen [Cu-N 2.014(4) angstrom] and 2 oxygens from the carboxylates of Hdips [Cu-01.951 (3) angstrom], with weaker off-axial bonds to carboxylate oxygens [Cu-O 2.557(3) angstrom]. The hydroxyl oxygen of Hdips is not co-ordinated. These complexes have been tested for antiviral and cytotoxic activity. Most are potently cytotoxic, especially [Cu(dmphen)(Hdips)2], where dmphen is 2,9-dimethylphenanthroline.

  DOI：

  10.1039/dt9930003393