| 154849-69-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 154849-69-1
• 化学式: C₁₈H₃₁O₄PSn
• 分子量: 461.125
• InChiKey: NLIMXIKPENYABC-SVZPRBGCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.62
• 重原子数：
  24.0
• 可旋转键数：
  9.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  52.6
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  、 三甲基溴硅烷 以 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  2,2-Functionally disubstituted organotin compounds: synthesis and reactivity

  摘要：

  A series of 2,2-difunctional organotin compounds of the general type Me(3)SnCH(2)CHXY (X, Y = P(O)R(2) or C(O)R; R = (OPr)-Pr-i, OEt or Ph) has been synthesized by stannylmethylation of the appropriate 2,2-difunctional methanides Na[CHXY] with iodomethyl trimethylstannane. Derivatives with phenyl groups on tin cannot be made by this method. The reactions of the title compounds at the tin atom and at the acidic CH group of the bridging carbon atom and modifications of the functional P(O)R(2) and C(O)R groups are described.

  DOI：

  10.1016/0022-328x(94)88031-x
• 作为产物：
  描述：

  、 trimethylstannylmethyl iodide 以 正庚烷 为溶剂， 以60-75的产率得到
  参考文献：
  名称：

  2,2-Functionally disubstituted organotin compounds: synthesis and reactivity

  摘要：

  A series of 2,2-difunctional organotin compounds of the general type Me(3)SnCH(2)CHXY (X, Y = P(O)R(2) or C(O)R; R = (OPr)-Pr-i, OEt or Ph) has been synthesized by stannylmethylation of the appropriate 2,2-difunctional methanides Na[CHXY] with iodomethyl trimethylstannane. Derivatives with phenyl groups on tin cannot be made by this method. The reactions of the title compounds at the tin atom and at the acidic CH group of the bridging carbon atom and modifications of the functional P(O)R(2) and C(O)R groups are described.

  DOI：

  10.1016/0022-328x(94)88031-x