3β-acetoxy-olean-12-en-28-oic acid hydrazide | 117864-99-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 3β-acetoxy-olean-12-en-28-oic acid hydrazide
• 英文别名: 3β-Acetoxy-olean-12-en-28-saeure-hydrazid
• CAS: 117864-99-0
• 化学式: C₃₂H₅₂N₂O₃
• 分子量: 512.776
• InChiKey: RCRRYUWCPKNQKY-DFHVBEEKSA-N

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 乙醚 、 肼 作用下， 生成 3β-acetoxy-olean-12-en-28-oic acid hydrazide
  参考文献：
  名称：

  Free hemoglobin concentrations in patients receiving massive blood transfusion during emergency surgery for trauma

  摘要：

  Purpose: To determine free hemoglobin concentration in patients who received massive blood transfusion during emergency surgery for trauma with consideration of the storage of the transfused blood.Methods: Fifteen patients undergoing emergency surgery for multiple trauma and who received blood transfusion of more than 5,000 mt were studied. Transfusion of the stored whole blood in citrate-phosphate glucose solution using a micropore filter was started before surgery. Serum concentrations of hemoglobin (total:THb and free:fHb) and total haptoglobin (THp) were measured until 5,000 mt of blood had been transfused. Serum free haptoglobin (fHp) concentration was calculated. The correlation between the changes in hemoglobin or haptoglobin concentrations and total storage days of the transfused blood was analyzed by a simple regression analysis.Results: Free hemoglobin was detected after 2,000 mt transfusion. The THp and fHp decreased after 1,000 mt transfusion. Total storage time (days) of transfused blood had correlated with the changes of THp (P < 0.0001) and fHp (P = 0.0027) but not with the changes of THb (P = 0.984) and fHb (P = 0.834).Conclusion: After blood transfusion during surgery for trauma, serum haptoglobin concentration decreased with transfusion of greater than or equal to 1,000 mt of whole blood with mean storage time of 12.2 dy. Free hemoglobin was detected after 2,000 mt transfusion when THp decreased to 1,000 mg L-l. Serum haptoglobin concentrations correlated negatively with storage time (days) of transfused blood.

  DOI：

  10.1007/bf03019668