teubrevin C | 107584-95-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: teubrevin C
• 英文别名: Teucryeminone
• CAS: 107584-95-2
• 化学式: C₂₄H₂₈O₉
• 分子量: 460.481
• InChiKey: UWRDCNVTKORVMI-QSQWZJICSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  33
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  122
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  6,20-bis-deacetylteupyreinidine 在 12-I-5-triacetoxyperiodinane 作用下， 以 二氯甲烷 为溶剂， 反应 3.5h， 以16 mg的产率得到teubrevin C
  参考文献：
  名称：

  Neo-clerodane diterpenoids fromTeucrium polium ssp.Aurasianum

  摘要：

  Five neo-clerodane diterpenes were isolated from the aerial parts of Teucrium polium ssp. aurasianum, One was known (teumicropodine) and the others were new: 3-deacetylteumicropodine, 3,20-bis-deacetylteupyreinidine, 6,20-bis-deacetylteupyreinidine and 3,6,20-tri-deacetylteupyreinidine. Their structures and absolute stereochemistry were elucidated by spectral and correlation techniques.

  DOI：

  10.1016/s0031-9422(00)89588-6

文献信息

• Neo-clerodane diterpenoids from teucrium lepicephalum and teucrium buxifolium
  作者：Giuseppe Savona、Franco Piozzi、Orietta Servettaz、Benjamin Rodriguez、Juan A. Hueso-Rodriguez、Maria C. De La Torre

  DOI：10.1016/s0031-9422(00)84512-4

  日期：1986.1

  Abstract Three new neo-clerodane diterpenoids, teulepicin, 19-acetylteulepicin and teulepicephin, have been isolated, together with the previously known flavone cirsiliol from the aerial parts of Teucrium lepicephalum . The structures of the diterpenoids were established by chemical and spectroscopic means and by correlation with known substances. In addition, 19-acetylteulepicin and the already known

  摘要 三种新的新克罗丹二萜类化合物 teulepicin、19-acetylteulepicin 和 teulepicephin，以及先前已知的黄酮 cirsiliol 从 Teucrium lepicephalum 地上部分被分离出来。二萜类化合物的结构是通过化学和光谱方法以及与已知物质的相关性确定的。此外，已从 T. buxifolium 物种中分离出 19-acetylteulepicin 和已知的新克罗丹二萜类化合物 19-acetylgnaphalin。
• Neo-clerodane diterpenoids from Teucrium micropodioldes
  作者：Maria C. De La Torre、Benjamín Rodríguez、Maurizio Bruno、Giuseppe Savona、Franco Piozzi、Orietta Servettaz

  DOI：10.1016/0031-9422(88)80616-2

  日期：——

  Abstract From the aerial parts of Teucrium micropodioides five new neo-clerodane diterpenoids, teumicropin, 3-acetylteumicropin, teumicropodin, deacetylteupyrenone and 3-deacetyl-20- epi -teulanigin, have been isolated. The structures of these substances were established by chemical and spectroscopic means and by correlation with known compounds.

  摘要 从 Teucrium micropodioides 的地上部分分离出五种新的新克罗丹二萜类化合物：teumicropin、3-acetylteumicropin、teumicropodin、deacetylteupyrenone 和 3-deacetyl-20-epi-teulanigin。这些物质的结构是通过化学和光谱方法以及与已知化合物的相关性确定的。
• Neo-clerodane diterpenoids fromTeucrium gracile
  作者：Maurizio Bruno、Gema Domi´nguez、Ana Lourenço、Franco Piozzi、Benjami´n Rodri´guez、Giuseppe Savona、Mari´a C. De la Torre、Nelly A. Arnold

  DOI：10.1016/0031-9422(91)80092-f

  日期：1991.1

  Four new neo-clerodane diterpenoids have been isolated from the aerial parts of Teucrium gracile. The structures of these compounds, 3-beta,19-diacetoxy-4-alpha,18;15,16-diepoxy-6-beta-hydroxy-neo-cleroda-13(16),14-dien-20,12S-olide (teugracilin A), 19-acetoxy-4-alpha,18;15,16-diepoxy-3-beta,6-beta-dihydroxy-neo-cleroda-13(16),14-dien-20,12S-olide (3-O-deacetylteugracilin A), 19-acetoxy-4-alpha,18;15,16-diepoxy-3-beta,6-alpha-dihydroxy-neo-cleroda-13(16),14-dien-20,12S-olide (teugracilin B) and 12-zeta,19-diacetoxy-4-alpha,18;15,16-diepoxy-neo-cleroda-13(16),14-diene-3-beta,6-alpha-diol (teugracilin C), were established by chemical and spectroscopic means. In addition, the already known neo-clerodane derivative teumicropodin [3-beta,19-diacetoxy-4-alpha,18;15,16-diepoxy-6-alpha-hydroxy-neo-cleroda-13(16),14-dien-20,12S-olide] has been isolated from the same source.