3-(4-bromobenzoyl)-5-phenyl-1,2,4-oxadiazole | 1403961-23-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-(4-bromobenzoyl)-5-phenyl-1,2,4-oxadiazole
• CAS: 1403961-23-8
• 化学式: C₁₅H₉BrN₂O₂
• 分子量: 329.153
• InChiKey: YSAGVGJCEXKNBX-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  4-溴苯乙酮 、 苯甲腈 在 硝酸 、 ytterbium(III) nitrate 作用下， 反应 1.17h， 以83%的产率得到3-(4-bromobenzoyl)-5-phenyl-1,2,4-oxadiazole
  参考文献：
  名称：

  Lanthanide nitrates as Lewis acids in the one-pot synthesis of 1,2,4-oxadiazole derivatives

  摘要：

  In this work we report the use of lanthanide nitrates [Ln(NO3)(3)] acting as catalyst in direct one-pot synthesis of 3-benzoyl- and 3-acetyl-1,2,4-oxadiazoles derivatives from ketones, nitriles and nitric acid. This is the first example of one-pot synthesis of benzoyl-and acetyl 1,2,4-oxadiazoles derivatives preparation using acetophenones derivates with electron-donator groups.

  DOI：

  10.1590/s0103-50532012005000002