3-Isopropylidene-4-[1-(2,4,6-trimethyl-phenyl)-meth-(Z)-ylidene]-dihydro-furan-2,5-dione | 53529-65-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 3-Isopropylidene-4-[1-(2,4,6-trimethyl-phenyl)-meth-(Z)-ylidene]-dihydro-furan-2,5-dione
• 英文别名: (4Z)-3-propan-2-ylidene-4-[(2,4,6-trimethylphenyl)methylidene]oxolane-2,5-dione
• CAS: 53529-65-0
• 化学式: C₁₇H₁₈O₃
• 分子量: 270.328
• InChiKey: TWQKZFWVZICWRW-ZSOIEALJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  20
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-Isopropylidene-4-[1-(2,4,6-trimethyl-phenyl)-meth-(Z)-ylidene]-dihydro-furan-2,5-dione 以 吡啶 为溶剂， 生成 3-Isopropylidene-4-[1-(2,4,6-trimethyl-phenyl)-meth-(E)-ylidene]-dihydro-furan-2,5-dione
  参考文献：
  名称：

  A convenient method for conversion of the Z-isomer to the E-isomer from a mixture containing both isomers of fulgides

  摘要：

  A new method for the conversion of the Z-isomer of unsymmetrical substituted bis-methylenesuccinic anhydrides, 'fulgides', to their geometrical E-isomers was achieved by heating the Z-isomer under reflux or a mixture of both isomers in pyridine to give the E-isomer in near quantitative yield. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)01514-9