tert-butyl-[(1S)-1-[(3R)-1,4-dioxaspiro[4.5]decan-3-yl]undecoxy]-diphenylsilane | 865851-15-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: tert-butyl-[(1S)-1-[(3R)-1,4-dioxaspiro[4.5]decan-3-yl]undecoxy]-diphenylsilane
• CAS: 865851-15-6
• 化学式: C₃₅H₅₄O₃Si
• 分子量: 550.897
• InChiKey: HMXWOCXVEYJAIC-JHOUSYSJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.54
• 重原子数：
  39
• 可旋转键数：
  15
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.66
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  tert-butyl-[(1S)-1-[(3R)-1,4-dioxaspiro[4.5]decan-3-yl]undecoxy]-diphenylsilane 在 sodium hydroxide 、 四丁基氟化铵 、 potassium carbonate 、 臭氧 、 三氟乙酸 、 copper(I) bromide 作用下， 以 四氢呋喃 、 吡啶 、 甲醇 、 水 为溶剂， 生成 (5R,6S)-6-hydroxyhexadecan-5-olide
  参考文献：
  名称：

  (R)-2,3-Cyclohexylideneglyceraldehyde, a novel template for stereoselective preparation of functionalized δ-lactones: synthesis of mosquito oviposition pheromone

  摘要：

  (R)-2,3-Cyclohexylideneglyceraldehyde 1 has been used to prepare functionalized delta-lactones. This was exemplified by a simple and efficient synthesis of the oviposition pheromone 10 of Culex pipens fatigans. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.07.063
• 作为产物：
  描述：

  叔丁基二苯基氯硅烷 、 (2R,3S)-1,2-cyclohexylidenetridecane-1,2,3-triol 在 咪唑 作用下， 生成 tert-butyl-[(1S)-1-[(3R)-1,4-dioxaspiro[4.5]decan-3-yl]undecoxy]-diphenylsilane
  参考文献：
  名称：

  (R)-2,3-Cyclohexylideneglyceraldehyde, a novel template for stereoselective preparation of functionalized δ-lactones: synthesis of mosquito oviposition pheromone

  摘要：

  (R)-2,3-Cyclohexylideneglyceraldehyde 1 has been used to prepare functionalized delta-lactones. This was exemplified by a simple and efficient synthesis of the oviposition pheromone 10 of Culex pipens fatigans. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.07.063

文献信息

• (R)-2,3-Cyclohexylideneglyceraldehyde, a novel template for stereoselective preparation of functionalized δ-lactones: synthesis of mosquito oviposition pheromone
  作者：Bhaskar Dhotare、Dibakar Goswami、Angshuman Chattopadhyay

  DOI：10.1016/j.tetlet.2005.07.063

  日期：2005.9

  (R)-2,3-Cyclohexylideneglyceraldehyde 1 has been used to prepare functionalized delta-lactones. This was exemplified by a simple and efficient synthesis of the oviposition pheromone 10 of Culex pipens fatigans. (c) 2005 Elsevier Ltd. All rights reserved.