5-Methyl-2-(3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl)benzene-1,3-diol | 35482-50-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 5-Methyl-2-(3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl)benzene-1,3-diol
• CAS: 35482-50-9
• 化学式: C₁₇H₂₂O₂
• 分子量: 258.36
• InChiKey: GKVOVXWEBSQJPA-UHFFFAOYSA-N

物化性质

• 沸点：
  414.3±45.0 °C(Predicted)
• 密度：
  1.073±0.06 g/cm3(Predicted)
• 溶解度：
  乙醇中≤30mg/ml；DMSO中≤30mg/ml；二甲基甲酰胺中≤30mg/ml

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• [EN] PROCESS FOR THE SYNTHESIS OF CANNABIDIOL AND INTERMEDIATES THEREOF<br/>[FR] PROCÉDÉ DE SYNTHÈSE DE CANNABIDIOL ET DE SES INTERMÉDIAIRES
  申请人：COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN OF S

  公开号：WO2021181420A1

  公开（公告）日：2021-09-16

  The present invention relates to process for the preparation of cannabidiol (A) from the coupling of (D) and (E) through the intermediates (C) and (D) starting from compound (B). The invention further relates to the novel compounds (B), (C), (D) and (E) and reagents used in this process. More specifically, this invention provides the manufacturing of Cannabidiol (A) in milligram to gram or kilogram scale.

  本发明涉及从化合物（B）出发，通过中间体（C）和（D），从（D）和（E）的偶联制备大麻二酚（A）的方法。该发明还涉及在该过程中使用的新化合物（B）、（C）、（D）和（E）以及试剂。更具体地说，本发明提供了以毫克至克或千克为单位生产大麻二酚（A）的方法。
• PROCESS FOR THE SYNTHESIS OF CANNABIDIOL AND INTERMEDIATES THEREOF
  申请人：Council of Scientific & Industrial Research, an Indian registered body incorporated under the Registration of Societies Act (Act XXI of 1860)

  公开号：EP3923917A1

  公开（公告）日：2021-12-22
• TREATMENT METHOD, COMPOUNDS, AND METHOD OF INCREASING TRPV2 ACTIVITY
  申请人：THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH

  公开号：US20180037528A1

  公开（公告）日：2018-02-08

  The present invention is directed to a method of treating a subject for a disease or disorder associated with Trpv2 activity. The present invention also relates to a compound having the following structure: where substituents A and Rx-R5 are as defined herein. Also disclosed is a composition and a method of increasing Trpv2 activity in a cell or tissue.
• US7179800B2
  申请人：——

  公开号：US7179800B2

  公开（公告）日：2007-02-20