p-nitrophenyl 2,3,5,6-tetra-O-benzoyl-β-D-galactofuranose | 108223-95-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: p-nitrophenyl 2,3,5,6-tetra-O-benzoyl-β-D-galactofuranose
• CAS: 108223-95-6
• 化学式: C₄₀H₃₁NO₁₂
• 分子量: 717.686
• InChiKey: RHSBEWFJVNJHFD-RUEZBPGOSA-N

物化性质

• 沸点：
  836.0±65.0 °C(Predicted)
• 密度：
  1.41±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.23
• 重原子数：
  53.0
• 可旋转键数：
  13.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  166.8
• 氢给体数：
  0.0
• 氢受体数：
  12.0

反应信息

• 作为反应物：
  描述：

  p-nitrophenyl 2,3,5,6-tetra-O-benzoyl-β-D-galactofuranose 在 sodium methylate 作用下， 以 甲醇 为溶剂， 生成 4-硝基苯基-β-D-呋喃半乳糖脂
  参考文献：
  名称：

  Non-natural aldofuranosides as substrates of a β-glucosidase

  摘要：

  Based on glycosidase inhibitory activities of some known 1,4-iminoalditols, four aldofuranosides, (4-nitro)phenyl beta-D-glucofuranoside, -beta-D-galactofuranoside, -alpha-L-idofuranoside and -alpha-L-altrofuranoside, were identified as possible substrates of glucosidases and galactosidases. Three of them were found to be accepted by the beta-glucosidase from Agrobacterium sp. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2004.11.027
• 作为产物：
  描述：

  苯甲酰氯 、 alkaline earth salt of/the/ methylsulfuric acid 在 吡啶 、 对甲苯磺酸 作用下， 以 甲苯 为溶剂， 生成 p-nitrophenyl 2,3,5,6-tetra-O-benzoyl-β-D-galactofuranose
  参考文献：
  名称：

  Non-natural aldofuranosides as substrates of a β-glucosidase

  摘要：

  Based on glycosidase inhibitory activities of some known 1,4-iminoalditols, four aldofuranosides, (4-nitro)phenyl beta-D-glucofuranoside, -beta-D-galactofuranoside, -alpha-L-idofuranoside and -alpha-L-altrofuranoside, were identified as possible substrates of glucosidases and galactosidases. Three of them were found to be accepted by the beta-glucosidase from Agrobacterium sp. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2004.11.027

文献信息

• Synthesis of p-nitrophenyl β-d-galactofuranoside. A convenient substrate for β-galactofuranosidase
  作者：Oscar Varela、Carla Marino、Rosa M. de Lederkremer

  DOI：10.1016/s0008-6215(00)90153-8

  日期：1986.11