N,N'-bis<4,5-di(octyloxy)-2-nitrophenyl>oxamide | 156777-93-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N,N'-bis<4,5-di(octyloxy)-2-nitrophenyl>oxamide
• 英文别名: N~1~,N~2~-Bis[2-nitro-4,5-bis(octyloxy)phenyl]ethanediamide；N,N'-bis(2-nitro-4,5-dioctoxyphenyl)oxamide
• CAS: 156777-93-4
• 化学式: C₄₆H₇₄N₄O₁₀
• 分子量: 843.114
• InChiKey: XWVPFPJSELXRJB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  16.7
• 重原子数：
  60
• 可旋转键数：
  34
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  187
• 氢给体数：
  2
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  N,N'-bis<4,5-di(octyloxy)-2-nitrophenyl>oxamide 在 palladium on activated charcoal 氢气 作用下， 以 乙醇 、 氯仿 为溶剂， 以27%的产率得到6,7-di(octyloxy)quinoxaline-2,3(1H,4H)-dione
  参考文献：
  名称：

  Crossley, Maxwell J.; Gorjian, Sargon; Sternhell, Sever, Australian Journal of Chemistry, 1994, vol. 47, # 4, p. 723 - 738

  摘要：

  DOI：
• 作为产物：
  描述：

  1,2-二(辛氧基)苯 在 硫酸 、 硝酸 、 铁粉 、 溶剂黄146 作用下， 以 乙酸酐 为溶剂， 反应 3.0h， 生成 N,N'-bis<4,5-di(octyloxy)-2-nitrophenyl>oxamide
  参考文献：
  名称：

  Crossley, Maxwell J.; Gorjian, Sargon; Sternhell, Sever, Australian Journal of Chemistry, 1994, vol. 47, # 4, p. 723 - 738

  摘要：

  DOI：

文献信息

• [EN] DISACCHARIDES FOR DRUG DISCOVERY<br/>[FR] DISACCHARIDES POUR LA DECOUVERTE DE MEDICAMENTS
  申请人：ALCHEMIA PTY LTD

  公开号：WO2003093286A1

  公开（公告）日：2003-11-13

  Methods are described for the preparation of combinatorial libraries of potentially biologically active disaccharide compounds. These compounds are variously functionalized, with a view to varying lipid solubility size, function and other properties, with the particular aim of discovering novel drug or drug-like compounds, or compounds with useful properties. The invention provides intermediates, processes and synthetic strategies for the solution or solid phase synthesis of disaccharides, variously functionalised about the sugar ring, including the addition of aromaticity and charge, and the placement of pharmaceutically useful groups and isosteres.

  描述了制备可能具有生物活性的二糖化合物组合库的方法。这些化合物通过各种方式进行了官能化，以改变脂溶性、大小、功能和其他性质，特别是为了发现新型的药物或类似药物化合物，或者具有有用性质的化合物。该发明提供了中间体、过程和合成策略，用于二糖的溶液或固相合成，包括在糖环周围进行不同的官能化，引入芳香性和电荷，以及放置药物上有用的基团和等电子体。
• Phase change inks containing gelator additives
  申请人：Xerox Corporation

  公开号：US20040065227A1

  公开（公告）日：2004-04-08

  Disclosed is a phase change ink composition comprising an ink vehicle, a colorant, and a nonpolymeric organic gelator selected from the group consisting of anthracene-based compounds, steroid compounds, partially fluorinated high molecular weight alkanes, high molecular weight alkanes with exactly one hetero atom, chiral tartrate compounds, chiral butenolide-based compounds, bis-urea compounds, guanines, barbiturates, oxamide compounds, ureidopyrimidone compounds, and mixtures thereof, said organic gelator being present in the ink in an amount of no more than about 20 percent by weight of the ink, said ink having a melting point at or below which the ink is a solid, said ink having a gel point at or above which the ink is a liquid, and said ink exhibiting a gel state between the melting point and the gel point, said ink exhibiting reversible transitions between the solid state and the gel state upon heating and cooling, said ink exhibiting reversible transitions between the gel state and the liquid state upon heating and cooling, said melting point being greater than about 35° C., said gel point being greater than said melting point. Also disclosed are imaging processes employing phase change inks containing gelator additives.

  本发明公开了一种相变油墨组合物，该组合物包含油墨载体、着色剂和非聚合有机凝胶剂，这些非聚合有机凝胶剂选自蒽类化合物、类固醇化合物、部分氟化的高分子量烷烃、含有一个杂原子的高分子量烷烃、手性酒石酸盐化合物、手性丁烯内酯类化合物、双脲化合物、鸟嘌呤、巴比妥酸盐、草酰胺化合物、脲基嘧啶酮化合物、手性酒石酸盐化合物、手性丁烯内酯化合物、双脲化合物、鸟嘌呤、巴比妥酸盐、草酰胺化合物、脲基嘧啶酮化合物及其混合物，所述有机凝胶剂在油墨中的含量不超过油墨重量的 20%、所述油墨的熔点为固态或低于熔点，所述油墨的凝胶点为液态或高于凝胶点，所述油墨在熔点和凝胶点之间呈现凝胶态，所述油墨在加热和冷却时在固态和凝胶态之间呈现可逆转换，所述油墨在加热和冷却时在凝胶态和液态之间呈现可逆转换，所述熔点高于约 35°C.,所述凝胶点大于所述熔点。还公开了采用含有凝胶剂添加剂的相变油墨的成像工艺。
• DISACCHARIDES FOR DRUG DISCOVERY
  申请人：Alchemia Limited

  公开号：EP1501844A1

  公开（公告）日：2005-02-02
• US6872243B2
  申请人：——

  公开号：US6872243B2

  公开（公告）日：2005-03-29
• Crossley, Maxwell J.; Gorjian, Sargon; Sternhell, Sever, Australian Journal of Chemistry, 1994, vol. 47, # 4, p. 723 - 738
  作者：Crossley, Maxwell J.、Gorjian, Sargon、Sternhell, Sever、Tansey, Kerrie M.

  DOI：——

  日期：——