Bpk6dnn4FW | 1841084-42-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Bpk6dnn4FW
• 英文别名: [(1R,2R)-2-[[(1R,2S,6R,7S)-3,5-dioxo-4-azatricyclo[5.2.1.02,6]decan-4-yl]methyl]cyclohexyl]methyl hydrogen sulfate
• CAS: 1841084-42-1
• 化学式: C₁₇H₂₅NO₆S
• 分子量: 371.5
• InChiKey: NEOOORXCXFXNGE-HGPDSQILSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  109
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• PROCESSES FOR MAKING ALKYLATED ARYLPIPERAZINE AND ALKYLATED ARYLPIPERIDINE COMPOUNDS INCLUDING NOVEL INTERMEDIATES
  申请人：Johnson Matthey Public Limited Company

  公开号：US20150361099A1

  公开（公告）日：2015-12-17

  Novel processes, and intermediates, for making alkylated arylpiperazine and alkylated arylpiperidine compounds of the general formulas (I) and (VII), respectively wherein, R 1 and R 2 are individually selected from hydrogen, alkyl, substituted or alkyl; n=0, 1, or 2; Y=NR 3 R 4 , OR 5 , or SR 5 , where R 3 and R 4 are individually selected from acyl or sulfonyl, and where R 5 is aryl or heteroaryl, or heterocyclic; and Ar is an aryl, heteroaryl, or heterocyclic compound.

  用于制备通式(I)和(VII)中所示的烷基化芳基哌嗪和烷基化芳基哌啶化合物的新工艺和中间体，其中，R1和R2分别选择自氢、烷基、取代基或烷基；n=0、1或2；Y=NR3R4、OR5或SR5，其中R3和R4分别选择自酰基或磺酰基，R5是芳基或杂芳基，或杂环烷基；Ar是芳基、杂芳基或杂环烷基。
• US9790237B2
  申请人：——

  公开号：US9790237B2

  公开（公告）日：2017-10-17
• US9957283B1
  申请人：——

  公开号：US9957283B1

  公开（公告）日：2018-05-01
• [EN] PROCESSES FOR MAKING ALKYLATED ARYLPIPERAZINE AND ALKYLATED ARYLPIPERIDINE COMPOUNDS INCLUDING NOVEL INTERMEDIATES<br/>[FR] PROCÉDÉS POUR LA FABRICATION DE COMPOSÉS D'ARYLPIPÉRAZINE ALKYLÉE ET D'ARYLPIPÉRIDINE ALKYLÉE COMPRENANT DE NOUVEAUX INTERMÉDIAIRES
  申请人：JOHNSON MATTHEY PLC

  公开号：WO2015195478A1

  公开（公告）日：2015-12-23

  Novel processes, and intermediates, for making alkylated arylpiperazine and alkylated arylpiperidine compounds of the general formulas (I) and (VII), respectively wherein, R1 and R2 are individually selected from hydrogen, alkyl, substituted or aikyl; n= 0, 1, or 2; Y = NR3R4, QR5, or SR5, where R3 and R4 are individually selected from acyl or su!fonyl, and where R5 is aryi or heteroaryi, or heterocyclic; and Ar is an aryl, heteroaryl, or heterocyclic compound.