| 1512846-77-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1512846-77-3
• 化学式: C₃₁H₅₀O₉Si
• 分子量: 594.818
• InChiKey: OGOFQHYWDGOPFY-CQIJDGOCSA-N

反应信息

• 作为产物：
  描述：

  1,5-anhydro-3-O-benzyl-4-O-(tert-butyldimethylsilyl)-2,6-dideoxy-D-ribo-hex-1-enitol 、 双丙酮半乳糖 在 [ReOCl3(OPPh3)(SMe2)] 作用下， 以 苯 为溶剂， 反应 12.0h， 以62.264%的产率得到
  参考文献：
  名称：

  Catalytic Stereoselective Synthesis of β-Digitoxosides: Direct Synthesis of Digitoxin and C1′-epi-Digitoxin

  摘要：

  A mild and atom-economic rhenium(V)-catalyzed stereoselective synthesis of beta-D-digitoxosides from 6-deoxy-D-allals has been described. This beta-selective glycosylation was achieved probably because of the formation of corresponding alpha-digitoxosides disfavored by 1,3-diaxial interaction. In addition, this method has been successfully applied to the synthesis of digitoxin trisaccharide glycal for the direct synthesis of digitwdn and C1'-epi-digitoxin.

  DOI：

  10.1021/jo4021419