(Z)-3-(bicyclo[2.2.1]heptan-2-yl)-5-[(5-(4'-methoxyphenyl)furan-2-yl)methylene]-2-thioxothiazolidin-4-one | 1149657-80-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (Z)-3-(bicyclo[2.2.1]heptan-2-yl)-5-[(5-(4'-methoxyphenyl)furan-2-yl)methylene]-2-thioxothiazolidin-4-one
• 英文别名: (5Z)-3-(2-bicyclo[2.2.1]heptanyl)-5-[[5-(4-methoxyphenyl)furan-2-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
• CAS: 1149657-80-6
• 化学式: C₂₂H₂₁NO₃S₂
• 分子量: 411.546
• InChiKey: XNUDJXBHERNWLZ-NDENLUEZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  100
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• [EN] TREATING AND PREVENTING VIRAL INFECTIONS<br/>[FR] TRAITEMENT ET PRÉVENTION D'INFECTIONS VIRALES
  申请人：UAB RESEARCH FOUNDATION

  公开号：WO2009059243A1

  公开（公告）日：2009-05-07

  Compounds that are useful in treating or preventing viral infections, such as influenza, are described herein. Further described are compositions made from these compounds and methods for using the compounds and their compositions in treating or preventing viral infections.

  本文描述了用于治疗或预防病毒感染（如流感）的化合物。进一步描述了由这些化合物制成的组合物以及使用这些化合物和它们的组合物来治疗或预防病毒感染的方法。
• TREATING AND PREVENTING VIRAL INFECTIONS
  申请人：The UAB Research Foundation

  公开号：EP2217573A1

  公开（公告）日：2010-08-18
• Treating and Preventing Viral Infections
  申请人：Luo Ming

  公开号：US20100286212A1

  公开（公告）日：2010-11-11

  Compounds that are useful in treating or preventing viral infections, such as influenza, are described herein. Further described are compositions made from these compounds and methods for using the compounds and their compositions in treating or preventing viral infections.
• COMPOUNDS USEFUL AS ANTIVIRAL AGENTS, COMPOSITIONS, AND METHODS OF USE
  申请人：Wang Guoxin

  公开号：US20130090339A1

  公开（公告）日：2013-04-11

  Novel 3-N-cycloalkyl-5-substituted-2-thioxothiazolidin-4-one derivatives that are effective for use in treating viral infections are described. Also described are pharmaceutical compositions comprising the 3-N-cycloalkyl-5-substituted-2-thioxothiazolidin-4-one derivatives and methods for using the compounds or compositions.
• US8466177B2
  申请人：——

  公开号：US8466177B2

  公开（公告）日：2013-06-18