| 1482520-32-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• CAS: 1482520-32-0
• 化学式: C₁₅H₁₄N₂O₃
• 分子量: 270.288
• InChiKey: VNKZAKAWWLYCCF-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  2-氨甲基吡啶 、 4-羟基香豆素 、 以 甲醇 为溶剂， 以82%的产率得到2,7-bis(2,3-dimethoxyphenyl)-6-(2-hydroxybenzoyl)-8a-(pyrazin-2-yl)-1-(pyrazine-2-carbonyl)-3-(pyridin-2-yl)hexahydroindolizin-5(1H)-one
  参考文献：
  名称：

  Metal-Free [3 + 2 + 1]/[2 + 2 + 1] Biscyclization: Stereospecific Construction with Concomitant Functionalization of Indolizin-5(1H)-one

  摘要：

  A metal-free [3 + 2 + 1]/[2 + 2 + 1] biscyclization strategy has been developed for the stereospecific construction with concomitant derivation of biologically significant indolizin-5(1H)-ones from simple and commercial starting materials. The transformations are notable because they can yield five new a bonds and six stereocenters including a quaternary carbon center in a single operation.

  DOI：

  10.1021/jo401969g