(3R,4S)-2,3-dimethylpentane-2,3,4-triol | 79418-10-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (3R,4S)-2,3-dimethylpentane-2,3,4-triol
• CAS: 79418-10-3；138257-37-1
• 化学式: C₇H₁₆O₃
• 分子量: 148.202
• InChiKey: KIWVFGZUYUZNKQ-CAHLUQPWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  60.7
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  二甲醇缩甲醛 、 (3R,4S)-2,3-dimethylpentane-2,3,4-triol 在 对甲苯磺酸 、 lithium bromide 作用下， 以 乙酸乙酯 为溶剂， 反应 7.0h， 生成 2-[(4R,5S)-4,5-dimethyl-1,3-dioxolan-4-yl]propan-2-ol 、 (5R,6S)-4,4,5,6-tetramethyl-1,3-dioxan-5-ol 、 (1S)-1-[(4R)-4,5,5-trimethyl-1,3-dioxolan-4-yl]ethanol
  参考文献：
  名称：

  Gras, J. L.; Poncet, A., Bulletin de la Societe Chimique de France, 1991, # 4, p. 566 - 573

  摘要：

  DOI：

文献信息

• THIOL-CONTAINING COMPOUNDS FOR THE REMOVAL OF ELEMENTS FROM TISSUES AND FORMULATIONS THEREFOR
  申请人：Haley Boyd E.

  公开号：US20110160150A1

  公开（公告）日：2011-06-30

  Methods and pharmaceutical formulations for ameliorating heavy metal toxicity and/or oxidative stress are disclosed, comprising administering pharmaceutically effective amounts of ligands according to the present disclosure. The ligands are of the general structure: where R 1 comprises benzene, pyridine, pyridin-4-one, naphthalene, anthracene, phenanthrene or alkyl groups, R 2 comprises hydrogen, alkyls, aryls, a carboxyl group, carboxylate esters, organic groups or biological groups, R 3 comprises alkyls, aryls, a carboxyl group, carboxylate esters, organic groups or biological groups, X comprises hydrogen, lithium, sodium, potassium, rubidium, cesium, francium, alkyls, aryls, a carboxyl group, carboxylate esters, thiophosphate, N-acetyl cysteine, mercaptoacetic acid, mercaptopropionic acid, thiolsalicylate, organic groups or biological groups, n independently equals 1-10, m=1-6, Y comprises hydrogen, polymers, silicas or silica supported substrates, and Z comprises hydrogen, alkyls, aryls, a carboxyl group, carboxylate esters, a hydroxyl group, NH 2 , HSO 3 , halogens, a carbonyl group, organic groups, biological groups, polymers, silicas or silica supported substrates.
• US8575218B2
  申请人：——

  公开号：US8575218B2

  公开（公告）日：2013-11-05
• Gras, J. L.; Poncet, A., Bulletin de la Societe Chimique de France, 1991, # 4, p. 566 - 573
  作者：Gras, J. L.、Poncet, A.

  DOI：——

  日期：——