(Z)-1-carboxy-2-phenyl-vinylmercury (1+); chloride | 856178-22-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: (Z)-1-carboxy-2-phenyl-vinylmercury (1+); chloride
• 英文别名: (Z)-1-Carboxy-2-phenyl-vinylquecksilber(1+); Chlorid；α-Chloromercurio-trans-zimtsaeure；(1-carboxy-2-phenylethenyl)-chloromercury
• CAS: 856178-22-8
• 化学式: C₉H₇ClHgO₂
• 分子量: 383.196
• InChiKey: YAWKHRTXIAEMFI-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  2.35
• 重原子数：
  13.0
• 可旋转键数：
  3.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  37.3
• 氢给体数：
  1.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  (Z)-1-carboxy-2-phenyl-vinylmercury (1+); chloride 在 lithium chloride 、 palladium dichloride 作用下， 以 甲醇 、 乙醚 为溶剂， 反应 2.0h， 生成 (Z,Z)-α,δ-Diphenylfulgensaeure-dimethylester
  参考文献：
  名称：

  Elbe,H.-L.; Koebrich,G., Chemische Berichte, 1974, vol. 107, p. 1654 - 1666

  摘要：

  DOI：
• 作为产物：
  描述：

  別桂皮酸 在 sodium hydroxide 作用下， 生成 (Z)-1-carboxy-2-phenyl-vinylmercury (1+); chloride
  参考文献：
  名称：

  Significant changes in the serum levels of IL-6, h-HGF, and type IV collagen 7S during the perioperative period of a hepatectomy: Relevance to SIRS

  摘要：

  We analyzed the changes in the serum levels of both interleukin-6 (IL-6), human hepatocyte growth factor (h-HGF), and type IV collagen 7S (7S) during the perioperative period of a hepatectomy and evaluated their relationship with systemic inflammatory response syndrome (SIRS), The study subjects consisted of 40 patients who underwent a hepatectomy, In 14 out of 40 patients, postoperative SIRS(+) was observed, Between the SIRS(+) and SIRS(-) cases, there were significant differences in the preoperative values of prothrombin time, hepaplastin test, cholinesterase, and indocyanine green retention at 15 min (P < 0.01). Compared with the SIRS(-) cases, the IL-6, h-HGF, and 7S of the SIRS(+) cases fluctuated in a higher range and remained significantly higher after postoperative day 1 (P < 0.05), Eight out of 14 SIRS(+) patients had postoperative complications, In the 8 SIRS(+) patients with postoperative complications and in the 4 patients in which the SIRS(+) state lasted 3 days or longer, the 7S levels were significantly higher during the perioperative period (P < 0.05), In the SIRS(+) cases, the postoperative levels of IL-6 and h-HGF, as well as pre- and postoperative levels of 7S, were elevated, We therefore consider these levels to be risk factors for complications during the perioperative period of a hepatectomy.

  DOI：

  10.1007/s005950050612

文献信息

• BANERJI, A.;GHOSAL, T., INDIAN J. CHEM., 1984, 23, N 5, 427-430
  作者：BANERJI, A.、GHOSAL, T.

  DOI：——

  日期：——