| 1030376-85-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• CAS: 1030376-85-2
• 化学式: C₄₁H₅₇F₃O₅
• 分子量: 686.896
• InChiKey: VHDBVDXIEZZQMR-IHLKIXASSA-N

反应信息

• 作为产物：
  描述：

  24R-hydroxy-3,4-seco-9βH-lanost-4(28),7,25(26)-trien-3-oic acid methyl ester 、 (R)-methoxytrifluoromethylphenylacetyl chloride 以 氘代吡啶 为溶剂， 反应 4.0h， 生成
  参考文献：
  名称：

  Lanostane-Type Triterpenoids from the Roots of Kadsura coccinea

  摘要：

  Seven new lanostane-type triterpenoids, seco-coccinic acids A-F (1-6) and coccinilactone A (7), were isolated from the roots of Kadsura coccinea. Their structures were established on the basis of spectroscopic data analysis. The absolute configuration at C-24 of compound 5 was confirmed by the modified Mosher's method. The cell growth inhibitory effects of these compounds were determined in human leukemia HL-60 cells, and it was found that compounds 1, 2, 3, and 5 exhibited antiproliferative effects with GI(50) values ranging from 6.8 to 42.1 mu M.

  DOI：

  10.1021/np7007522