1-[4,4-Dichloro-3-methyl-1-(4-methylphenyl)but-1-enyl]-4-methylbenzene | 298714-46-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 1-[4,4-Dichloro-3-methyl-1-(4-methylphenyl)but-1-enyl]-4-methylbenzene
• CAS: 298714-46-2
• 化学式: C₁₉H₂₀Cl₂
• 分子量: 319.274
• InChiKey: YPOCJPFSVJEYBH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1-[4,4-Dichloro-3-methyl-1-(4-methylphenyl)but-1-enyl]-4-methylbenzene 在 四氯化钛 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 作用下， 生成 1,4-Dimethyl-1a-p-tolyl-1,1a-dihydro-cyclopropa[a]indene
  参考文献：
  名称：

  Cyclopropane-shift type reaction of diaryl(2-halogenocyclopropyl)methanols promoted by Lewis acids

  摘要：

  Novel cyclopropane-shift type reaction of diaryl(2-halogenocyclopropyl)methanols 2b and 7 proceeded by using BF3. OEt2 and TiCl4, respectively. Utilizing these reactions, 1-aryl-3-chloro-1,2-methanoindans 5 and 9, 1-aryl-3-methylnaphthalenes 6, and 1,2-methano-1-arylindens 10 were constructed. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)00979-5
• 作为产物：
  描述：

  ((1S,2S,3R)-2-Chloro-3-methyl-cyclopropyl)-di-p-tolyl-methanol 在 四氯化钛 作用下， 以69%的产率得到1-[4,4-Dichloro-3-methyl-1-(4-methylphenyl)but-1-enyl]-4-methylbenzene
  参考文献：
  名称：

  Cyclopropane-shift type reaction of diaryl(2-halogenocyclopropyl)methanols promoted by Lewis acids

  摘要：

  Novel cyclopropane-shift type reaction of diaryl(2-halogenocyclopropyl)methanols 2b and 7 proceeded by using BF3. OEt2 and TiCl4, respectively. Utilizing these reactions, 1-aryl-3-chloro-1,2-methanoindans 5 and 9, 1-aryl-3-methylnaphthalenes 6, and 1,2-methano-1-arylindens 10 were constructed. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)00979-5