(1R)-(+)-Camphor formaldehyde azine | 779352-60-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (1R)-(+)-Camphor formaldehyde azine
• CAS: 779352-60-2
• 化学式: C₁₁H₁₈N₂
• 分子量: 178.277
• InChiKey: QOZHOZGQIXAHGT-KCJUWKMLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.89
• 重原子数：
  13.0
• 可旋转键数：
  1.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  24.72
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  sodium tetrachloropalladate(II) 、 (1R)-(+)-Camphor formaldehyde azine 以 甲醇 为溶剂， 以69%的产率得到trans-[PdCl2((1R)-(+)-camphor formaldehyde azine)2]
  参考文献：
  名称：

  Palladium complexes of azines, α-diazines and α-2-pyridylazines containing (1R)-(+)-camphor or (1R)-(–)-fenchone groups

  摘要：

  Mixed monoazines of types H2C=N-N=C10H16 [C10H16 is a (1R)-(+)-camphor residue (L(1)), or a (1R)-(-)-fenchone residue (L(2))] or Me(2)C=N-N=C10H16 [C10H16 is a (1R)-(+)-camphor residue (L(3))], or alpha-diazines C10H16=N-N=CH-CH=N-N=C10H16 [C10H16 is a (1R)-(+)-camphor residue (L(4)) or a (1R)-(-)-fenchone residue (L(5))], or alpha-2-pyridyl azines C10H16=N-N=CHC5H4N [C10H16 is a (1R)-(+)-camphor residue (L(6)) or a (1R)-(-)-fenchone residue (L(7))] reacted with Na2PdCl4 to give compounds of type [PdCl(2)L(2)(n)] for L(1), L(2) or L(3) as monodentate nitrogen-donor ligands and chelated mononuclear complexes of the type [PdCl(2)L(n)] for L(4), L(5), L(6) or L(7). The complexes of the monodentate azines L(1) and L(2) exist in solution as mixtures of isomers differing in the ligating nitrogens. The compounds L(1), L(2) and L(4)-L(7) also reacted with [Pd2Cl4(PR(3))(2)] to give [PdCl2(PR(3))L(n)] (n=1, R(3)=Me(2)Ph or Me(2)(C(6)H(4)OMe-4); n=2, R(3)=Me(2)Ph, Me(2)(C(6)H(4)OMe-4) or Ph(3); n=4 or 5, R(3)=Me(2)Ph; n=6, R(3)=Bu(3)(n); n=7, R(3)=Bu(3)(n), or Me(2)Ph), in which the ligands are monodentate, or [{PdCl2(PR(3))}(2)L(n)] (L(n)=L(4)-L(7), R(3)=Me(2)Ph), in which the ligands are bidentate bridging. The phosphine complexes were characterised in solution but were isolated only for [PdCl2(PR(3))L(n)] (L(n)=L(6), R(3)=Bu(3)(n); L(7), R(3)=Bu(3)(n) or Me(2)Ph; L(2), R(3)=Ph(3)). Compounds L(4), L(6) or L(7) reacted with the eta(3)-methylallylpalladium complex [{PdCl(eta(3)-CH(2)CMeCH(2))}(2)] and NH4PF6 to give [Pd(eta(3)-CH(2)CMeCH(2))L(n)]PF6 (L(n)=L(4), L(6) or L(7)). The crystal structure of [PdCl(2)L(6)]. 0.5CH(2)Cl(2) was determined by X-ray diffraction analysis: the crystals are monoclinic, space group P2(1) with a=9.5830(13), b=13.9720(14) and c=14.726(2) Angstrom, beta=97.610(11)degrees and Z=4. It shows two molecules of the complex in the asymmetric unit differing only in the torsion angles around the N-N bond.

  DOI：

  10.1039/dt9950001697
• 作为产物：
  描述：

  聚合甲醛 、 (+)-camphor hydrazone 在 甲酸 、 sodium sulfate 作用下， 以 二氯甲烷 为溶剂， 以68%的产率得到(1R)-(+)-Camphor formaldehyde azine
  参考文献：
  名称：

  Palladium complexes of azines, α-diazines and α-2-pyridylazines containing (1R)-(+)-camphor or (1R)-(–)-fenchone groups

  摘要：

  Mixed monoazines of types H2C=N-N=C10H16 [C10H16 is a (1R)-(+)-camphor residue (L(1)), or a (1R)-(-)-fenchone residue (L(2))] or Me(2)C=N-N=C10H16 [C10H16 is a (1R)-(+)-camphor residue (L(3))], or alpha-diazines C10H16=N-N=CH-CH=N-N=C10H16 [C10H16 is a (1R)-(+)-camphor residue (L(4)) or a (1R)-(-)-fenchone residue (L(5))], or alpha-2-pyridyl azines C10H16=N-N=CHC5H4N [C10H16 is a (1R)-(+)-camphor residue (L(6)) or a (1R)-(-)-fenchone residue (L(7))] reacted with Na2PdCl4 to give compounds of type [PdCl(2)L(2)(n)] for L(1), L(2) or L(3) as monodentate nitrogen-donor ligands and chelated mononuclear complexes of the type [PdCl(2)L(n)] for L(4), L(5), L(6) or L(7). The complexes of the monodentate azines L(1) and L(2) exist in solution as mixtures of isomers differing in the ligating nitrogens. The compounds L(1), L(2) and L(4)-L(7) also reacted with [Pd2Cl4(PR(3))(2)] to give [PdCl2(PR(3))L(n)] (n=1, R(3)=Me(2)Ph or Me(2)(C(6)H(4)OMe-4); n=2, R(3)=Me(2)Ph, Me(2)(C(6)H(4)OMe-4) or Ph(3); n=4 or 5, R(3)=Me(2)Ph; n=6, R(3)=Bu(3)(n); n=7, R(3)=Bu(3)(n), or Me(2)Ph), in which the ligands are monodentate, or [{PdCl2(PR(3))}(2)L(n)] (L(n)=L(4)-L(7), R(3)=Me(2)Ph), in which the ligands are bidentate bridging. The phosphine complexes were characterised in solution but were isolated only for [PdCl2(PR(3))L(n)] (L(n)=L(6), R(3)=Bu(3)(n); L(7), R(3)=Bu(3)(n) or Me(2)Ph; L(2), R(3)=Ph(3)). Compounds L(4), L(6) or L(7) reacted with the eta(3)-methylallylpalladium complex [{PdCl(eta(3)-CH(2)CMeCH(2))}(2)] and NH4PF6 to give [Pd(eta(3)-CH(2)CMeCH(2))L(n)]PF6 (L(n)=L(4), L(6) or L(7)). The crystal structure of [PdCl(2)L(6)]. 0.5CH(2)Cl(2) was determined by X-ray diffraction analysis: the crystals are monoclinic, space group P2(1) with a=9.5830(13), b=13.9720(14) and c=14.726(2) Angstrom, beta=97.610(11)degrees and Z=4. It shows two molecules of the complex in the asymmetric unit differing only in the torsion angles around the N-N bond.

  DOI：

  10.1039/dt9950001697