(4E)-3,5-diphenylpent-4-enoic acid methyl ester | 337368-37-3

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物
• 英文名称: (4E)-3,5-diphenylpent-4-enoic acid methyl ester
• 英文别名: methyl (E)-3,5-diphenylpent-4-enoate
• CAS: 337368-37-3
• 化学式: C₁₈H₁₈O₂
• 分子量: 266.34
• InChiKey: HSSGVQJJISFROM-OUKQBFOZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  20
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (4E)-3,5-diphenylpent-4-enoic acid methyl ester 在 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 以95%的产率得到(E)-3,5-diphenylpent-4-en-1-ol
  参考文献：
  名称：

  合作Ñ -杂环卡宾/乙烯基溴化物钯催化极性转换1,4-加成到Enals

  摘要：

  通过NHC /钯协同催化，可以将高度溴化的1,4-乙烯基立体选择性的乙烯基溴加到烯醛上，从而以优异的收率（高达90％）生成各种有价值的γ，δ-不饱和羰基衍生物。详细的机理研究表明，NHC在该系统中既充当有机催化剂又充当钯的配体。

  DOI：

  10.1021/acs.orglett.0c03654
• 作为产物：
  描述：

  以 乙醇 为溶剂， 反应 1.5h， 以98%的产率得到(4E)-3,5-diphenylpent-4-enoic acid methyl ester
  参考文献：
  名称：

  Casey; Gairns; Walker, Synlett, 2000, # 12, p. 1725 - 1728

  摘要：

  DOI：

文献信息

• Rhodium-Catalyzed Reaction of Aryl- and Alkenylboronic Acids with 2,4-Dienoate Esters:  Conjugate Addition and Heck Reaction Products
  作者：Gabriela de la Herrán、Carmen Murcia、Aurelio G. Csákÿ

  DOI：10.1021/ol0522485

  日期：2005.12.1

  [chemical reaction: see text]. We report herein the first examples of the addition of aryl- and alkenylboronic acids catalyzed by RhI complexes to 2,4-dienoate esters. Three different types of products have been obtained depending on the substitution pattern of the starting ester and the organoboronic acid: 1,6-conjugate addition products, 1,4-conjugate addition products, and Heck reaction products

  [化学反应：见正文]。我们在本文中报道了由RhI络合物催化的芳基-和烯基硼酸加成到2，4-二烯酸酯中的第一个实例。根据起始酯和有机硼酸的取代方式，已获得三种不同类型的产物：1，6-共轭加成产物，1，4-共轭加成产物和Heck反应产物。
• Rhenium complex-catalyzed carbon-carbon formation of alcohols and organosilicon compounds
  作者：Rui Umeda、Toshifumi Jikyo、Kazuki Toda、Issey Osaka、Yutaka Nishiyama

  DOI：10.1016/j.tetlet.2018.02.019

  日期：2018.3

  The coupling reactions of allylic and benzylic alcohols and allyltrimethylsilane are efficiently catalyzed by a rhenium complex to give the corresponding 1,5-dienes and alkenes in moderate to good yields. Similarly, alcohols were coupled with ketene silyl acetals to form the corresponding esters.

  a络合物可有效催化烯丙基和苄醇与烯丙基三甲基硅烷的偶联反应，以中等至良好的收率得到相应的1,5-二烯和烯烃。类似地，将醇与乙烯酮甲硅烷基缩醛偶联以形成相应的酯。
• Compositional dependence of elastic properties and density of glasses in the system anorthite-diopside-forsterite
  作者：Frank R. Schilling

  DOI：10.1007/s004100100253

  日期：2001.6

  The compressional (nu (P)) and shear (nu (S)) wave velocities of 20 glasses in the pseudoternary system anorthite (An)-diopside (Di)-forsterite (Fo) were measured by Brillouin spectroscopy as a means of constraining the effect of composition on the elasticity of glasses. The velocity data together with measured densities were used to calculate the elastic properties: Young's modulus (E), adiabatic bulk modulus (K-S) shear modulus (G), and Poisson's ratio (sigma). The data show that different chemical constituents affect the density, velocities and elastic properties in a highly systematic way. All of the properties we examined are well described by ideal mixing of molar properties. The addition of MgO strongly increases the bulk, Young's and shear moduli. The results are compared to different models describing the elastic properties of glasses as a function of chemical composition. We show that the influence of magnesia is underestimated in previous models, in some cases due to a lack of appropriate experimental data. The relatively large values of elastic moduli for magnesia-rich glasses can be explained by the high bonding strength between magnesium and SiO4 and AlO4 tetrahedra. The strongest effect of magnesium is on the bulk modulus, the shear modulus is less affected. Therefore, Poisson's ratio shows a modest increase with increasing MgO content. The observed increase of poisson's ratio with increasing MgO content may be explained by a reduced bond strength between tetrahedra due to the addition of MgO.
• Cross-Coupling Reaction of Oxo-π-allylnickel Complex Generated from 1,3-Diene under an Atmosphere of Carbon Dioxide
  作者：Masanori Takimoto、Miwako Mori

  DOI：10.1021/ja004004f

  日期：2001.3.1