triethyl phosphonoacetate anion | 38868-10-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物
• 英文名称: triethyl phosphonoacetate anion
• 英文别名: triethylphosphonoacetate；diethoxyphosphoryl-acetic acid ethyl ester; anion
• CAS: 38868-10-9
• 化学式: C₈H₁₆O₅P
• 分子量: 223.186
• InChiKey: SNBCZNABMJUYMS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.98
• 重原子数：
  14.0
• 可旋转键数：
  7.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  61.83
• 氢给体数：
  0.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  3-phenylpent-2-en-4-ynal 、 triethyl phosphonoacetate anion 以78%的产率得到ethyl (2E,4E)-5-phenylhepta-2,4-dien-6-ynoate
  参考文献：
  名称：

  Synthesis and properties of bisdehydro[4n+2]annulenediones

  摘要：

  DOI：

  10.1016/s0040-4039(01)81981-x
• 作为产物：
  描述：

  磷酰基乙酸三乙酯 在 sodium hydride 作用下， 以 四氢呋喃 、 paraffin 为溶剂， 生成 triethyl phosphonoacetate anion
  参考文献：
  名称：

  Cardiotonic steroids. 5. A synthesis of bufadienolides and cardenolides from 3.beta.-acetoxy-5-androsten-17-one via common intermediates

  摘要：

  DOI：

  10.1021/jo00171a018

文献信息

• An efficient synthesis of yuehchukene
  作者：Jyh-Horng Sheu、Yua-Kuang Chen、Yen-Long Vincent Hong

  DOI：10.1016/s0040-4039(00)74483-2

  日期：1991.2

  A three-step synthesis of yuehchukene 1, a novel dimeric indole natural product with anti-implantation activity via acid-catalyzed reaction of β-(3-hydroxy-3-methylbutenyl)indole is reported.

  报导了三步合成yuehchukene 1，这是一种新型的二聚吲哚天然产物，它通过酸催化β-（3-羟基-3-甲基丁烯基）吲哚的反应具有抗植入活性。
• Joshi, N..N.; Mamdapur, V. R.; Chadha, M. S., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1984, vol. 23, # 3, p. 238 - 240
  作者：Joshi, N..N.、Mamdapur, V. R.、Chadha, M. S.

  DOI：——

  日期：——
• Ferreira, Aurelio B. B.; Salisbury, Kingsley, Journal of the Chemical Society. Perkin transactions II, 1982, p. 25 - 30
  作者：Ferreira, Aurelio B. B.、Salisbury, Kingsley

  DOI：——

  日期：——
• Design and synthesis of macro-heterocycles structurally related to tirofiban
  作者：Mahesh Ramaseshan、Martin Robitaille、John W Ellingboe、Yves L Dory、Pierre Deslongchamps

  DOI：10.1016/s0040-4039(00)00709-7

  日期：2000.6

  Sequences of nine and four steps were designed to yield two tirobifan related macrocycles by SN2 macrocyclization. The cyclic compounds contain the amino acid tyrosine, one insaturation and are either 18- or 20-membered rings. All the reaction conditions are very mild and the overall yields indicate that the results depend a lot on the structure of the targets and on the length of the reaction sequence. (C) 2000 Published by Elsevier Science Ltd.
• Niyazymbetov, Murat E.; Rongfeng, Zhou; Evans, Dennis H., Journal of the Chemical Society. Perkin transactions II, 1996, # 9, p. 1957 - 1962
  作者：Niyazymbetov, Murat E.、Rongfeng, Zhou、Evans, Dennis H.

  DOI：——

  日期：——