4-(4-Chlorophenyl)-1,2-diphenylbut-2-ene-1,4-dione | 53476-32-7

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物
• 英文名称: 4-(4-Chlorophenyl)-1,2-diphenylbut-2-ene-1,4-dione
• CAS: 53476-32-7
• 化学式: C₂₂H₁₅ClO₂
• 分子量: 346.813
• InChiKey: PNZSYMGEZQXESH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-(4-Chlorophenyl)-1,2-diphenylbut-2-ene-1,4-dione 在 甲醇 、 三氯硅烷 、 三苯基氧化膦 作用下， 以 1,2-二氯乙烷 为溶剂， 生成 5-(4-chlorophenyl)-2,3-diphenylfuran
  参考文献：
  名称：

  Successively Recycle Waste as Catalyst: A One-Pot Wittig/1,4-Reduction/Paal–Knorr Sequence for Modular Synthesis of Substituted Furans

  摘要：

  A one-pot tandem Wittig/conjugate reduction/PaalKnorr reaction is reported for the synthesis of di- or trisubstituted furans. This novel sequence first demonstrates the possibility of successively recycling waste from upstream steps to catalyze downstream reactions.

  DOI：

  10.1021/acs.orglett.5b00442
• 作为产物：
  描述：

  联苯甲酰 、 4-chlorobenzoylmethylenetriphenylphosphorane 以 甲苯 为溶剂， 反应 36.0h， 生成 4-(4-Chlorophenyl)-1,2-diphenylbut-2-ene-1,4-dione
  参考文献：
  名称：

  Successively Recycle Waste as Catalyst: A One-Pot Wittig/1,4-Reduction/Paal–Knorr Sequence for Modular Synthesis of Substituted Furans

  摘要：

  A one-pot tandem Wittig/conjugate reduction/PaalKnorr reaction is reported for the synthesis of di- or trisubstituted furans. This novel sequence first demonstrates the possibility of successively recycling waste from upstream steps to catalyze downstream reactions.

  DOI：

  10.1021/acs.orglett.5b00442

文献信息

• Synthesis of cyclic nitrone and 1,2-oxazine from 1,2,4-triaryl-but-2-ene-1,4-dione and hydroxylamine
  作者：MUTHUPANDI NAGARAJ、MURUGAN INIYA、MUTHUSAMY BOOMINATHAN、SHANMUGAM MUTHUSUBRAMANIAN、NATTAMAI BHUVANESH

  DOI：10.1007/s12039-012-0276-7

  日期：2012.7

  The reaction of hydroxylamine hydrochloride with differently substituted phenyldibenzoylethylene has been investigated. Both cyclic nitrone and 1,2-oxazine have been isolated and characterized by one- and two-dimensional NMR data and also by single crystal X-ray analysis. The reaction of hydroxylamine hydrochloride with differently subtituted phenyldibenzoylethylene has been investigated. Both cyclic

  已经研究了羟胺盐酸盐与不同取代的苯基二苯甲酰基乙烯的反应。环状硝酮和1,2-恶嗪均已分离，并通过一维和二维NMR数据以及单晶X射线分析进行了表征。 已经研究了羟胺盐酸盐与不同取代的苯基二苯甲酰基乙烯的反应。环状硝酮和1,2-恶嗪均已分离，并通过一维和二维NMR数据以及单晶X射线分析进行了表征。