Lanosterol | 854819-14-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Lanosterol
• 英文别名: Lanosterin；Tirucallol；Lanosta-8,24-dien-3-ol；4,4,10,13,14-pentamethyl-17-(6-methylhept-5-en-2-yl)-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
• CAS: 854819-14-0
• 化学式: C₃₀H₅₀O
• 分子量: 426.726
• InChiKey: CAHGCLMLTWQZNJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.9
• 重原子数：
  31
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• [EN] PROCESS FOR THE PREPARATION OF LANOSTA-8-ENE COMPOU<br/>[FR] PROCÉDÉ DE PRÉPARATION DE COMPOSÉS LANOSTA-8-ÈNES
  申请人：AMAZONIA FITOMEDICAMENTOS LTDA

  公开号：WO2010015875A1

  公开（公告）日：2010-02-11

  The present invention concerns a process for the preparation of lanosta-8-ene compounds having lanosta-8-ene-7-one or lanosta-8-ene-7-ol compounds as starting material.

  本发明涉及一种以lanosta-8-ene-7-one或lanosta-8-ene-7-ol化合物为起始原料制备lanosta-8-ene化合物的方法。
• PHARMACEUTICAL USES OF LANOSTA-8,24-DIEN-3-OLS
  申请人：Amazonia Fitomedicamentos Ltda

  公开号：EP2323666B1

  公开（公告）日：2017-01-04
• PHARMACEUTICAL USE OF MULTICYCLIC COMPOUNDS AS ANTI-AIDS AGENTS
  申请人：Amazonia Fitomedicamentos Ltda

  公开号：EP2523663A1

  公开（公告）日：2012-11-21
• Pharmaceutical Uses of Lanosta-8,24-dien-3-ols
  申请人：Pianowski Luiz Francisco

  公开号：US20110136773A1

  公开（公告）日：2011-06-09

  The invention generally refers to pharmaceutical uses of lanosta-8,24-dien-3-ols, a family of tetracyclic terpenols, as anti-inflammatory, anticancerigenous and analgesic agents via the inhibition of the disordered activation of serine-threonine protein kinases, particularly PKC.
• Pharmaceutical Use of Multicyclic Compounds as Anti-Aids Agents
  申请人：Pianowski Luiz Francisco

  公开号：US20120289487A1

  公开（公告）日：2012-11-15

  This invention refers to pharmaceutical use of multicyclic compounds chosen from ingenols, lanosta-8,24-dien-3-ols and their mixtures, as anti-AIDS agents.