2-Chloro-5,8-dihydroxy-3-(3-methyl-2-butenyl)-1,4-naphthalenedione, 9CI

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 2-Chloro-5,8-dihydroxy-3-(3-methyl-2-butenyl)-1,4-naphthalenedione, 9CI
• 英文别名: 2-chloro-5,8-dihydroxy-3-(3-methylbut-2-enyl)naphthalene-1,4-dione
• 化学式: C₁₅H₁₃ClO₄
• 分子量: 292.71
• InChiKey: CRNOJRLIVCGQAY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• METHOD OF THE ISOLATING CHLOROSESAMONE OR CHLOROSESAMONE-CONTAINING FRACTION FROM ROOTS OF GENUS SESAMUM, AND APPLICATION OF THE FRACTION THEREOF
  申请人：Brilliant Biomedical Corp.

  公开号：US20200290943A1

  公开（公告）日：2020-09-17

  This invention discovers a purification method for isolating an extract containing chlorosesamone from roots of genus Sesamum plants, and its application. In this invention, D 2 fraction containing chlorosesamone is obtained through an extraction step and a separation step. Then, through further purification step, chlorosesamone is obtained. In the experiment of this invention, D 2 fraction or chlorosesamone extracted from roots of Sesamum indicum , a plant of genus Sesamum, can be used for the anticancer treatment for cancer cells of breast, liver, blood and lung.