3-Benzoyl-4-methoxy-8,8-dimethyl-1,5,7-tris(3-methylbut-2-enyl)bicyclo[3.3.1]non-3-ene-2,9-dione

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 3-Benzoyl-4-methoxy-8,8-dimethyl-1,5,7-tris(3-methylbut-2-enyl)bicyclo[3.3.1]non-3-ene-2,9-dione
• 化学式: C₃₄H₄₄O₄
• 分子量: 516.7
• InChiKey: GKTNXDRETXZNOS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.6
• 重原子数：
  38
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  60.4
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] BICYCLO[3.3.1]NONENES USEFUL FOR THE TREATMENT OF DIABETES<br/>[FR] UTILISATION DES BICYCLO[3.3.1]NONENES POUR LE TRAITEMENT DE DIABETES
  申请人：SHAMAN PHARMACEUTICALS INC

  公开号：WO2000054760A2

  公开（公告）日：2000-09-21

  Bicyclo[3.3.1]nonenes, pharmaceutical compositions containing the nonenes and methods of using the compounds and compositions as hypoglycemic or hypotriglyceridemic agents are described. The bicyclo[3.3.1]nonenes and corresponding compositions are useful for lowering blood glucose levels, treating hyperglycemia and treating diabetes. The nonenes and corresponding compositions are also useful for lowering serum triglyceride levels and treating hypertriglyceridemia.