Zaluzanin C-acetat | 1212210-53-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Zaluzanin C-acetat
• 英文别名: (3,6,9-Trimethylidene-2-oxo-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-8-yl) acetate
• CAS: 1212210-53-1
• 化学式: C₁₇H₂₀O₄
• 分子量: 288.343
• InChiKey: GKMFOEIZCLMZDE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• USE OF LAURUS NOBILIS EXTRACT FRACTIONS TO PROTECT AGAINST AIR POLLUTION RELATED DISEASES
  申请人：DSM IP Assets B.V.

  公开号：US20220160804A1

  公开（公告）日：2022-05-26

  The present invention relates to systemic detoxification and chronic inflammation by using extract fractions of Laurus nobilis , that lead to a decrease of anti-inflammatory markers in human lung cell lines and the activation of the Nrf2 pathway, which is a crucial element in intracellular detoxification pathways, decreases the expression of inflammatory cytokines. Therefore, the extract can be used to reduce the adverse effects of air pollution generally (and especially of particulate air pollution), which includes: cardiovascular problems, respiratory diseases, and chronic inflammation of tissues that come into contact with air borne particles.
• [EN] USE OF LAURUS NOBILIS EXTRACT FRACTIONS TO PROTECT AGAINST AIR POLLUTION RELATED DISEASES<br/>[FR] UTILISATION DE FRACTIONS D'EXTRAIT DE LAURUS NOBILIS POUR LA PROTECTION CONTRE LES MALADIES LIÉES À LA POLLUTION DE L'AIR
  申请人：DSM IP ASSETS BV

  公开号：WO2020156908A1

  公开（公告）日：2020-08-06

  The present invention relates to systemic detoxification and chronic inflammation by using extract fractions of Laurus nobilis, that lead to a decrease of anti-inflammatory markers in human lung cell lines and the activation of the Nrf2 pathway, which is a crucial element in intracellular detoxification pathways, decreases the expression of inflammatory cytokines. Therefore, the extract can be used to reduce the adverse effects of air pollution generally (and especially of particulate air pollution), which includes: cardiovascular problems, respiratory diseases, and chronic inflammation of tissues that come into contact with air borne particles.