18-nor-abietane | 873382-41-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 18-nor-abietane
• 英文别名: 18-Nor-abietan；Fichtelit, 1a-Dimethyl-7-isopropyl-perhydro-phenantren；7-Isopropyl-1,4a-dimethyltetradecahydrophenanthrene；4b,8-dimethyl-2-propan-2-yl-2,3,4,4a,5,6,7,8,8a,9,10,10a-dodecahydro-1H-phenanthrene
• CAS: 873382-41-3
• 化学式: C₁₉H₃₄
• 分子量: 262.479
• InChiKey: HTNCYKZTYXSRHL-UHFFFAOYSA-N

物化性质

• 沸点：
  330.6±9.0 °C(Predicted)
• 密度：
  0.882±0.06 g/cm3(Predicted)
• 保留指数：
  1936

计算性质

• 辛醇/水分配系数(LogP)：
  7.7
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  二甲基环已酮 在 硫酸 、 镍 、 甲基环己烷 作用下， 225.0 ℃ 、14.71 MPa 条件下， 生成 18-nor-abietane
  参考文献：
  名称：

  THE SYNTHESIS OF 12-METHYLPERHYDRORETENE (ABIETANE) AND ITS NON-IDENTITY WITH FICHTELITE

  摘要：

  DOI：

  10.1021/jo01213a003

文献信息

• The Sustained Impact of an Evidenced-Based Clinical Pathway for Acute Appendicitis
  作者：Brad W. Warner、Kate A. Rich、Harry Atherton、Charlotte L. Andersen、Uma R. Kotagal

  DOI：10.1053/spsu.2002.29364

  日期：2002.2

  Appendicitis is a frequent pediatric surgical condition for which there is great variability among practitioners regarding diagnosis and postoperative management. With this in mind, the authors designed and implemented an evidence-based appendicitis clinical pathway at their institution. Establishment of the pathway resulted in decreased hospital cost, reduced hospital stay, and fewer unnecessary laboratory tests. The purpose of the current study was to determine the sustainability of the pathway beyond its initial implementation phase. The authors showed that several, but not all, favorable outcomes of the pathway were sustained. These data suggest that a clinical pathway for appendicitis at the authors' institution results in sustained beneficial effects in some but not all outcome parameters. Ongoing monitoring of pathway compliance, continued education of practitioners and nursing personnel, and identification of key pathway team member(s) responsible for the pathway system might result in a greater long-term impact of these guidelines.
• Hydrogenated phenanthrene homologs
  申请人：TORSTEN HASSELSTROM

  公开号：US02095548A1

  公开（公告）日：1937-10-12
• THE SYNTHESIS OF 12-METHYLPERHYDRORETENE (ABIETANE) AND ITS NON-IDENTITY WITH FICHTELITE
  作者：EDWARD CANFIELD STERLING、MARSTON TAYLOR BOGERT

  DOI：10.1021/jo01213a003

  日期：1939.3