2,8-Dimethyl-2-(4,8,12-trimethyltridec-11-enyl)chroman-6-ol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 2,8-Dimethyl-2-(4,8,12-trimethyltridec-11-enyl)chroman-6-ol
• 英文别名: 2,8-dimethyl-2-(4,8,12-trimethyltridec-11-enyl)-3,4-dihydrochromen-6-ol
• 化学式: C₂₇H₄₄O₂
• 分子量: 400.6
• InChiKey: IVNXPOCZLRVUIH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.5
• 重原子数：
  29
• 可旋转键数：
  11
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• SYNERGISTIC INTERACTION OF AT LEAST ONE VITAMIN E COMPONENT AND TYROSINASE INHIBITORS FOR DERMATOLOGICAL APPLICATIONS
  申请人：Davos Life Science Pte. Ltd.

  公开号：EP2558102A1

  公开（公告）日：2013-02-20
• [EN] SYNERGISTIC INTERACTION OF AT LEAST ONE VITAMIN E COMPONENT AND TYROSINASE INHIBITORS FOR DERMATOLOGICAL APPLICATIONS<br/>[FR] INTERACTION SYNERGIQUE D'AU MOINS UN CONSTITUANT DE VITAMINE E ET D'INHIBITEURS DE TYROSINASE POUR APPLICATIONS DERMATOLOGIQUES
  申请人：DAVOS LIFE SCIENCE PTE LTD

  公开号：WO2011129765A1

  公开（公告）日：2011-10-20

  The present invention is directed to a method of treating a dermatological condition or preventing a dermatological condition from occurring or for altering the pigmentation of the skin by administering to a patient a pharmaceutically effective amount of a composition comprising at least one Vitamin E component and at least one additional component different from the Vitamin E component that has anti-tyrosinase activity and/or anti-melanogenesis activity. The present invention is further directed to a pharmaceutical composition comprising at least one Vitamin E component and at least one additional component different from the Vitamin E component that has anti-tyrosinase activity and/or anti-melanogenesis activity.