α-cyperone | 60026-22-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: α-cyperone
• 英文别名: (+)-4,11-Eudesmadien-3-one；1,4a-dimethyl-7-prop-1-en-2-yl-3,4,5,6,7,8-hexahydronaphthalen-2-one
• CAS: 60026-22-4
• 化学式: C₁₅H₂₂O
• 分子量: 218.339
• InChiKey: KUFXJZXMWHNCEH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  α-cyperone 、 对甲苯磺酰肼 生成 N-[(E)-(1,4a-dimethyl-7-prop-1-en-2-yl-3,4,5,6,7,8-hexahydronaphthalen-2-ylidene)amino]-4-methylbenzenesulfonamide
  参考文献：
  名称：

  MIMURA TETSUYA; NAKAI TAKESHI, CHEM. LETT, 1980, NO 9, 1099-1102

  摘要：

  DOI：

文献信息

• BIOACTIVE COMPOSITION FOR THE TREATMENT OF THE HIV/AIDS, METHOD FOR MANUFACTURING AND USING THE SAME
  申请人：Shukla Mukesh Harilal

  公开号：US20110003841A1

  公开（公告）日：2011-01-06

  The present invention is about a bioactive composition for the treatment of HIV, particularly by the removal of the most prominent HIV antigen glycoproteins. The present invention further relates to the method for making and using such composition.
• SESQUITERPENOID-BASED COMPOUNDS, EXTRACTS OF CYPERUS ROTUNDUS COMPRISING THE SAME, AND USE THEREOF
  申请人：RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY

  公开号：US20150110901A1

  公开（公告）日：2015-04-23

  The present invention relates to a novel use of sesquiterpenoid compounds, the pharmaceutically acceptable salts thereof, or the extracts of Cyperus rotundus comprising same or the fractions thereof in the prevention or treatment of menopausal diseases. The sesquiterpenoid compound according to the present invention, the extracts of Cyperus rotundus comprising the same or fractions thereof exhibit excellent estrogenic activity or anti-allergic activity, and therefore they can be used for the prevention or treatment of menopausal diseases caused by a decline in estrogen level or by allergic diseases.
• US9795649B2
  申请人：——

  公开号：US9795649B2

  公开（公告）日：2017-10-24