leoheteronin D | 79434-22-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: leoheteronin D
• 英文别名: Labda-13-ene-8,15-diol；1-(5-hydroxy-3-methylpent-3-enyl)-2,5,5,8a-tetramethyl-3,4,4a,6,7,8-hexahydro-1H-naphthalen-2-ol
• CAS: 79434-22-3
• 化学式: C₂₀H₃₆O₂
• 分子量: 308.505
• InChiKey: LEOHDQKUMQKLMP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Method for biocatalytic production of terpene compounds
  申请人：FIRMENICH SA

  公开号：US11214775B2

  公开（公告）日：2022-01-04

  Provided herein are biocatalytic methods of producing terpene compounds by applying a novel type of phosphatase enzyme. The method allows the fully biochemical synthesis of terpene compounds, like for example copalol and labdendiol, and derivatives thereof, which serve as valuable intermediates for the production of perfumery ingredients, such as, for example, ambrox. Also provided are novel fully biochemical multistep processes for the production of such compounds as well as novel phosphatase enzymes and mutants and variants derived therefrom.

  本文提供了通过应用一种新型磷酸酶生产萜烯化合物的生物催化方法。这种方法可以完全生化合成萜烯化合物，例如 copalol 和 labdendiol 及其衍生物，它们是生产香水成分（例如 ambrox）的重要中间体。此外，还提供了生产此类化合物的新型全生化多步骤工艺，以及新型磷酸酶和由其衍生的突变体和变体。
• METHOD FOR BIOCATALYTIC PRODUCTION OF TERPENE COMPOUNDS
  申请人：Firmenich SA

  公开号：EP3821023A1

  公开（公告）日：2021-05-19
• [EN] METHOD FOR BIOCATALYTIC PRODUCTION OF TERPENE COMPOUNDS<br/>[FR] PROCÉDÉ DE PRODUCTION BIOCATALYTIQUE DE COMPOSÉS TERPÉNIQUES
  申请人：FIRMENICH & CIE

  公开号：WO2020011883A1

  公开（公告）日：2020-01-16

  Provided herein are biocatalytic methods of producing terpene compounds by applying a novel type of phosphatase enzyme. The method allows the fully biochemical synthesis of terpene compounds, like for example copalol and labdendiol, and derivatives thereof, which serve as valuable intermediates for the production of perfumery ingredients, such as, for example, ambrox. Also provided are novel fully biochemical multistep processes for the production of such compounds as well as novel phosphatase enzymes and mutants and variants derived therefrom.