1(7)-Terpinen-4-ol | 18479-63-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 1(7)-Terpinen-4-ol
• 英文别名: 4-Methylidene-1-propan-2-ylcyclohexan-1-ol
• CAS: 18479-63-5
• 化学式: C₁₀H₁₈O
• 分子量: 154.252
• InChiKey: OCWKXVANBBPRFP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Improved method of preparing cineoles
  申请人：Union Camp Corporation

  公开号：EP0270023A1

  公开（公告）日：1988-06-08

  A method is provided for preparing cineoles in an improved yield and with increased 1,4-cineole content, by reaction of terpin hydrate, terpineol or mixtures thereof with an acid, such as 50% sulfuric acid or 85% phosphoric acid, in the presence of a solvent for cineole which solvent is immiscible with the aqueous acid phase of the reaction mixture, and separating the cineole-containing solvent layer from the acid.

  本发明提供了一种方法，通过将水合萜品、松油醇或其混合物与酸，如 50%硫酸或 85% 磷酸，在松油醇溶剂的存在下进行反应，并将含松油醇的溶剂层与反应混合物的酸性水相分离，从而制备出产率更高且 1,4-松油醇含量更高的松油醇。
• Method of preparing cineoles
  申请人：Union Camp Corporation

  公开号：EP0300117B1

  公开（公告）日：1993-08-04
• THERAPEUTIC AGENTS
  申请人：The Boots Company PLC

  公开号：EP0539372A1

  公开（公告）日：1993-05-05
• US4831163A
  申请人：——

  公开号：US4831163A

  公开（公告）日：1989-05-16
• [EN] COMPOSITIONS OF MONOTERPENOIDS FOR THE TREATMENT OF AN HIV INFECTION<br/>[FR] MÉTHODE POUR LE TRAITEMENT D'UNE INFECTION À VIH
  申请人：REYNOLDS MAX

  公开号：WO2012104567A1

  公开（公告）日：2012-08-09

  The invention concerns use of a composition for the treatment and prophylaxis of an HIV infection in a patient. The composition comprises a mixture of 30% - 80% of at least one compound having the formula (I) and 10% to 40% of at least one compound of the formula (II) wherein the substituents are as defined in the description. The invention also relates to methods for the treatment and prophylaxis of an HIV infection and also use of the composition in the preparation of a medicament for treatment of an HIV infection.