hederagenin

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: hederagenin
• 英文别名: Wilforol C；10-hydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
• 化学式: C₃₀H₄₈O₄
• 分子量: 472.709
• InChiKey: PGOYMURMZNDHNS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  34
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  77.8
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• [EN] APPLICATIONS OF HEDERAGENIN AND DERIVATIVE OR SALT OF HEDERAGENIN IN PREPARATION OF DRUGS FOR TREATING OSTEOARTHRITIS<br/>[FR] APPLICATIONS D'HEDERAGÉNINE ET DE DÉRIVÉ OU DE SEL D'HEDERAGÉNINE DANS LA PRÉPARATION DE MÉDICAMENTS POUR LE TRAITEMENT DE L'ARTHROSE<br/>[ZH] 常春藤皂苷元及其衍生物或其盐在制备治疗骨性关节炎药物中的应用
  申请人：GUANGZHOU BOJI MEDICAL BIOTECHNOLOGICAL CO LTD

  公开号：WO2019075865A1

  公开（公告）日：2019-04-25

  本发明公开了具有通式(I)所示的常春藤皂苷元及其衍生物或其盐在制备治疗骨性关节炎药物中的应用；式（I）其中，R1和R2相同或不同，彼此独立的表示H或-CO(CH2)nCOOH，n＝1-3； R3为H、Na、K或NH3。
• Novel inhibitors of bacterial biofilms and related methods
  申请人：Sequoia Sciences, Inc.

  公开号：EP2712863B1

  公开（公告）日：2014-10-22
• Triterpene Compounds which are Effective on Improvement of Brain Function
  申请人：Choi Wonrack

  公开号：US20070249711A1

  公开（公告）日：2007-10-25

  The present invention relates to the triterpene compounds improving in brain functions. In particular, the present invention relates to a novel use of the triterpene compounds represented by the Formula 1 for improving decreased memory and a pharmaceutical composition for improving brain functions comprising the triterpene compounds represented by the Formula 1.
• TRITERPENE COMPOUNDS WHICH ARE EFFECTIVE ON IMPROVEMENT OF BRAIN FUNCTION
  申请人：CHOI Wonrack

  公开号：US20100099763A1

  公开（公告）日：2010-04-22

  The present invention relates to the triterpene compounds improving in brain functions. In particular, the present invention relates to a novel use of the triterpene compounds represented by the Formula 1 for improving decreased memory and a pharmaceutical composition for improving brain functions comprising the triterpene compounds represented by the Formula 1.
• US8790687B2
  申请人：——

  公开号：US8790687B2

  公开（公告）日：2014-07-29