5-{[4,5-Dihydroxy-6-(hydroxymethyl)-3-[(3,4,5-trihydroxy-6-methyloxan-2-YL)oxy]oxan-2-YL]oxy}-3,4-dihydroxy-6-{[9-hydroxy-4-(hydroxymethyl)-4,6A,6B,8A,11,11,14B-heptamethyl-1,2,3,4A,5,6,7,8,9,10,12,12A,14,14A-tetradecahydropicen-3-YL]oxy}oxane-2-carboxylic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 5-{[4,5-Dihydroxy-6-(hydroxymethyl)-3-[(3,4,5-trihydroxy-6-methyloxan-2-YL)oxy]oxan-2-YL]oxy}-3,4-dihydroxy-6-{[9-hydroxy-4-(hydroxymethyl)-4,6A,6B,8A,11,11,14B-heptamethyl-1,2,3,4A,5,6,7,8,9,10,12,12A,14,14A-tetradecahydropicen-3-YL]oxy}oxane-2-carboxylic acid
• 英文别名: 5-[4,5-dihydroxy-6-(hydroxymethyl)-3-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxy-3,4-dihydroxy-6-[[9-hydroxy-4-(hydroxymethyl)-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]oxane-2-carboxylic acid
• 化学式: C₄₈H₇₈O₁₈
• 分子量: 943.1
• InChiKey: PTDAHAWQAGSZDD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  66
• 可旋转键数：
  9
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  295
• 氢给体数：
  11
• 氢受体数：
  18

文献信息

• Oleanene-type triterpene glycosides as masking agents
  申请人：Symrise AG

  公开号：EP2559346A1

  公开（公告）日：2013-02-20

  The present invention relates to the use of certain oleanene-type triterpene glycosides of formula (I) and/or physiologically acceptable salts thereof wherein M is hydrogen or hydroxyl, preferably hydroxyl, and A is a carbohydrate moiety, preferably an oligosaccharide moiety, for modifying (i.e. modulating) or masking (i.e. reducing or suppressing) unpleasant taste impressions, in particular bitter and/or astringent taste impressions and to a corresponding method for modulating or masking an unpleasant taste of a substance or substance mixture. The present invention also relates to compositions, in particular orally consumable compositions, comprising (a) one or more compounds of formula (I) or a physiologically acceptable salt thereof, and (b) one or more substances with unpleasant taste, in particular bitter and/or astringent taste.

  本发明涉及式 (I) 的某些齐墩果烯型三萜苷和/或其生理上可接受的盐的用途 其中 M 是氢或羟基，最好是羟基，以及 A 是碳水化合物分子，最好是寡糖分子、 用于改变（即调节）或掩盖（即减少或抑制）不愉快的味道印象，特别是苦味和/或涩味印象，以及用于调节或掩盖物质或物质混合物的不愉快味道的相应方法。 本发明还涉及组合物，特别是口服组合物，包括(a)一种或多种式(I)化合物或其生理上可接受的盐，和(b)一种或多种具有令人不快的味道，特别是苦味和/或涩味的物质。
• [EN] OLEANENE-TYPE TRITERPENE GLYCOSIDES AS MASKING AGENTS<br/>[FR] GLYCOSIDES TRITERPÉNIQUES DE TYPE OLÉANÈNE EN TANT QU'AGENTS DE MASQUAGE
  申请人：SYMRISE AG

  公开号：WO2013023891A1

  公开（公告）日：2013-02-21

  The present invention relates to the use of certain oleanene-type triterpene glycosides of formula (I) and/or physiologically acceptable salts thereof formula (I) wherein M is hydrogen or hydroxyl, preferably hydroxyl, and A is a carbohydrate moiety, preferably an oligosaccharide moiety, for modifying (i.e. modulating) or masking (i.e. reducing or suppressing) unpleasant taste impressions, in particular bitter and/or astringent taste impressions and to a corresponding method for modulating or masking an unpleasant taste of a substance or substance mixture. The present invention also relates to compositions, in particular orally consumable compositions, comprising (a) one or more compounds of formula (I) or a physiologically acceptable salt thereof, and (b) one or more substances with unpleasant taste, in particular bitter and/or astringent taste.