Phosphono (1,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl) hydrogen phosphate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Phosphono (1,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl) hydrogen phosphate
• 化学式: C₁₀H₂₀O₇P₂
• 分子量: 314.21
• InChiKey: VZPAJODTZAAANV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  113
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• 1-deoxy-D-xylulose 5-phosphate synthase alleles responsible for enhanced terpene biosynthesis
  申请人：Genoplante-Valor

  公开号：EP2444416A1

  公开（公告）日：2012-04-25

  This invention relates to a method of enhancement of the 1-deoxy-D-xylulose 5-phosphate synthase (DXS) activity of plants or bacteria to increase terpenes production in cells. The invention also relates to an enhanced DXS sequence likely to be obtained by this method. This invention also relates to a method of enhancement of production of terpenes in a host cell containing the enhanced DXS enzyme. Finally the invention relates to transgenic bacterium or plants that express this polypeptide.

  本发明涉及一种增强植物或细菌的 1-脱氧-D-木酮糖 5-磷酸合成酶（DXS）活性以增加细胞中萜烯生产的方法。 本发明还涉及一种可能通过该方法获得的增强 DXS 序列。 本发明还涉及一种在含有增强型 DXS 酶的宿主细胞中提高萜烯产量的方法。 最后，本发明还涉及表达这种多肽的转基因细菌或植物。
• 1-Deoxy-D-xylulose 5-phosphate synthase alleles responsible for enhanced terpene biosynthesis
  申请人：Genoplante-Valor

  公开号：EP2444415A1

  公开（公告）日：2012-04-25

  This invention relates to new polypeptides having a 1-deoxy-D-xylulose 5-phosphate synthase (DXS) activity, which polypeptides comprise a sequence having at least 90 % identity with the sequence SEQ ID N° 1 or fragments thereof. These polypeptides are responsible of a massive accumulation of terpenes in cells. The invention also relates to transgenic plants, bacteria or yeast that express this polypeptide, and capable of a greatly enhanced accumulation of terpenes, in comparison to plants, bacteria or yeast expressing a typical DXS gene. The invention also relates to a method of production of terpenes by culturing transgenic plants, bacteria or yeast that express this polypeptide. Finally the invention relates to transgenic plants that express this polypeptide, and resistant to clomazone.

  本发明涉及具有 1-脱氧-D-木酮糖 5-磷酸合成酶（DXS）活性的新多肽，这些多肽的序列与序列 SEQ ID N° 1 或其片段至少有 90% 的相同性。这些多肽能使细胞中的萜烯大量积累。 本发明还涉及表达这种多肽的转基因植物、细菌或酵母，与表达典型 DXS 基因的植物、细菌或酵母相比，它们能够大大提高萜类化合物的积累。 本发明还涉及一种通过培养表达这种多肽的转基因植物、细菌或酵母来生产萜烯的方法。 最后，本发明还涉及表达这种多肽并对氯马宗具有抗性的转基因植物。
• Terpene synthases from ylang ylang (Cananga odorata var. fruticosa)
  申请人：TEMASEK LIFE SCIENCES LABORATORY LIMITED

  公开号：US10266837B2

  公开（公告）日：2019-04-23

  The present invention relates to the field of plant molecular biology. More particularly, the present invention relates to the isolation of nucleic acids encoding terpene synthases (TPSs), including a novel, multifunctional TPS identified herein as CoTPS2.

  本发明涉及植物分子生物学领域。更具体地说，本发明涉及萜烯合成酶（TPSs）编码核酸的分离，包括一种新型多功能 TPS，即 CoTPS2。
• Production of cyclic terpenoids
  申请人：——

  公开号：US20020142408A1

  公开（公告）日：2002-10-03

  A methanotrophic bacterium has been genetically engineered to produce cyclic terpenoids from geranyl pyrophosphate.

  对一种甲烷营养细菌进行了基因工程改造，使其能够利用焦磷酸香叶酯生产环状萜类化合物。
• MONOTERPENE SYNTHASES FROM COMMON SAGE ($i(SALVIA OFFICINALIS))
  申请人：WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION

  公开号：EP1017788A1

  公开（公告）日：2000-07-12