alpha-Tocomonoenol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: alpha-Tocomonoenol
• 英文别名: 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridec-11-enyl)-3,4-dihydrochromen-6-ol
• 化学式: C₂₉H₄₈O₂
• 分子量: 428.7
• InChiKey: ZYCUYLKDCYFZAS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.2
• 重原子数：
  31
• 可旋转键数：
  11
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.72
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• SYNERGISTIC INTERACTION OF AT LEAST ONE VITAMIN E COMPONENT AND TYROSINASE INHIBITORS FOR DERMATOLOGICAL APPLICATIONS
  申请人：Davos Life Science Pte. Ltd.

  公开号：EP2558102A1

  公开（公告）日：2013-02-20
• JPH08277282A
  申请人：——

  公开号：JPH08277282A

  公开（公告）日：1996-10-22
• MICROPARTICLES FOR USE IN IMMUNOGENIC COMPOSITIONS
  申请人：Malyala Padma

  公开号：US20110280949A1

  公开（公告）日：2011-11-17

  Immunogenic compositions are disclosed which comprise microparticles that comprise a biodegradable polymer, an immunological adjuvant and a tocol-family compound. Methods of making and using such microparticle compositions are also disclosed.
• [EN] SYNERGISTIC INTERACTION OF AT LEAST ONE VITAMIN E COMPONENT AND TYROSINASE INHIBITORS FOR DERMATOLOGICAL APPLICATIONS<br/>[FR] INTERACTION SYNERGIQUE D'AU MOINS UN CONSTITUANT DE VITAMINE E ET D'INHIBITEURS DE TYROSINASE POUR APPLICATIONS DERMATOLOGIQUES
  申请人：DAVOS LIFE SCIENCE PTE LTD

  公开号：WO2011129765A1

  公开（公告）日：2011-10-20

  The present invention is directed to a method of treating a dermatological condition or preventing a dermatological condition from occurring or for altering the pigmentation of the skin by administering to a patient a pharmaceutically effective amount of a composition comprising at least one Vitamin E component and at least one additional component different from the Vitamin E component that has anti-tyrosinase activity and/or anti-melanogenesis activity. The present invention is further directed to a pharmaceutical composition comprising at least one Vitamin E component and at least one additional component different from the Vitamin E component that has anti-tyrosinase activity and/or anti-melanogenesis activity.