endo N-ethylbornylamine | 839716-26-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: endo N-ethylbornylamine
• 英文别名: Aethyl-<(1R)-bornyl>-amin；ethyl-((1R)-bornyl)-amine；Aethyl-((1R)-bornyl)-amin；Aethyl-((1R)-bornyl)-amin; Aethylbornylamin；(1R,2S,4R)-N-ethyl-1,7,7-trimethylbicyclo[2.2.1]heptan-2-amine
• CAS: 839716-26-6
• 化学式: C₁₂H₂₃N
• 分子量: 181.321
• InChiKey: MXTFOPRRJZPMRN-SCVCMEIPSA-N

物化性质

• 沸点：
  209.1±8.0 °C(Predicted)
• 密度：
  0.91±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  endo N-ethylbornylamine 生成 benzoylethylbornylamine
  参考文献：
  名称：

  Forster, Journal of the Chemical Society, 1899, vol. 75, p. 943

  摘要：

  DOI：
• 作为产物：
  描述：

  溴乙烷 、 alkaline earth salt of/the/ methylsulfuric acid 在 氢氧化钾 、 乙醇 、 水 作用下， 生成 endo N-ethylbornylamine
  参考文献：
  名称：

  Forster, Journal of the Chemical Society, 1899, vol. 75, p. 943

  摘要：

  DOI：

文献信息

• The effects of added ammonium chloride in the reductive amination of some carbonyl compounds over Ru and Pd catalysts
  作者：Tomoaki Ikenaga、Kumiko Matsushita、Junichi Shinozawa、Satoru Yada、Yuzuru Takagi

  DOI：10.1016/j.tet.2004.12.062

  日期：2005.2

  The reductive amination of acetophenone, (+)-camphor, and 5alpha-cholestan-3-one over Ru and Pd metals as well as their carbon-supported catalysts gave corresponding amines together with alcohols as by-products. However, we found that the corresponding amines are selectively synthesized by the addition of ammonium chloride to the reaction system with depression of the formation of alcohol, as exemplified with acetophenone. Although alcohols are usually not formed over Pd with alicyclic ketones, the alcohols formation was effectively depressed over Ru in the presence of ammonium chloride. The effects of the additive on the stereoselectivity of the formation of amines are also discussed in the cases of (+)-camphor and 5alpha-cholestan-3-one. (C) 2005 Published by Elsevier Ltd.
• Gryszkiewicz-Trochimowski, Roczniki Chemii, 1934, vol. 14, p. 335,337
  作者：Gryszkiewicz-Trochimowski

  DOI：——

  日期：——
• Forster; Attwell, Journal of the Chemical Society, 1904, vol. 85, p. 1190
  作者：Forster、Attwell

  DOI：——

  日期：——
• Forster, Journal of the Chemical Society, 1899, vol. 75, p. 943
  作者：Forster

  DOI：——

  日期：——