cyanidin 3-O-D-galactoside | 47705-70-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: cyanidin 3-O-D-galactoside
• 英文别名: cyanidin 3-O-galactoside；cyanidin-3-O-galactoside；Cyanidin 3-galactoside；cyanidin-3-galactoside；cyanidin-3-O-gal；ideain；(3R,4S,5R,6R)-2-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromenylium-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
• CAS: 47705-70-4；142506-26-1
• 化学式: C₂₁H₂₁O₁₁
• 分子量: 449.391
• InChiKey: RKWHWFONKJEUEF-WYFQJXRYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  0.38
• 重原子数：
  32
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  181
• 氢给体数：
  8
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  cyanidin 3-O-D-galactoside 在 盐酸 作用下， 以 甲醇 、 水 为溶剂， 反应 0.5h， 生成 花色素
  参考文献：
  名称：

  Effects of Aronia melanocarpa Constituents on Biofilm Formation of Escherichia coli and Bacillus cereus

  摘要：

  许多生长在物体表面的细菌会形成生物膜。这种结构中微生物的适应性和基因变化使它们对抗菌剂产生抗药性。医疗器械上形成生物膜的微生物会对人类健康造成严重威胁。因此，需要新的预防和治疗策略。本研究旨在评估 Aronia melanocarpa 提取物、亚组分和化合物在体外防止生物膜形成和抑制大肠杆菌和蜡样芽孢杆菌细菌生长的能力。研究发现，几种 aronia 物质具有抗生物膜活性，但对所筛选的物种没有毒性。与传统抗菌剂相比，这种无毒抑制作用可能会降低产生抗药性的可能性。

  DOI：

  10.3390/molecules181214989
• 作为产物：
  描述：

  尿苷 5’-二二氧磷基半乳糖二钠盐 、 花色素 在 3-O-glycosyltransferase from Scutellaria baicalensis 作用下， 以 aq. buffer 为溶剂， 反应 1.0h， 生成 cyanidin 3-O-D-galactoside
  参考文献：
  名称：

  黄cut的高度混杂类黄酮3- O-糖基转移酶

  摘要：

  从黄cut中发现了一种高度区域特异性和供体混杂的3- O-糖基转移酶Sb3GT1（UGT78B4）。Sb3GT1可以接受五个糖供体（UDP-Glc / -Gal / -GlcNAc / -Xyl / -Ara）催化17种黄酮醇的3- O-糖基化，转化率可以> 98％。通过按比例放大的酶催化作用获得了五种新的糖苷。分子建模和定点诱变表明，G15和P187是供体滥交的关键催化残基。Sb3GT1可能是增加类黄酮3- O-糖苷结构多样性的有前途的催化剂。

  DOI：

  10.1021/acs.orglett.9b00524

文献信息

• Encapsulated Vaccinium Extracts with Balanced Gastrointestinal Release
  申请人：Siegel Sven

  公开号：US20090041872A1

  公开（公告）日：2009-02-12

  The invention relates to Vaccinium fruit extracts, related preparations, production methods and uses.

  本发明涉及蓝莓属水果提取物、相关制剂、生产方法及其用途。
• Formation of Stable Pyranoanthocyanins, and Uses Thereof as Sources of Natural Color
  申请人：Ohio State Innovation Foundation

  公开号：US20180346731A1

  公开（公告）日：2018-12-06

  Described herein are chromophore compounds formed by interaction of ascorbic acid (AA) and a pyranoanthocyanin (PACN) compound. Also described herein are natural food colorant compositions that include chromophore compounds. The pyranoanthocyanins can be formed by the heterocyclic addition of the C4 and 5-OH of an anthocyanin, using a polar metabolite. Also described herein are pyranoanthocyanins, and methods of making and using the same.

  本文描述了由抗坏血酸（AA）和吡喃类花青素（PACN）化合物相互作用形成的色团化合物。还描述了包括色团化合物的天然食品着色剂组合物。可以通过使用极性代谢产物对花青素的C4和5-OH进行杂环加成来形成吡喃类花青素。本文还描述了吡喃类花青素的制备和使用方法。
• METHOD FOR MODIFYING POLYPHENOL CONTAINING PLANT MATERIALS AND MEDICAL USES OF MODIFIED POLYPHENOL PLANT CONTAINING MATERIALS
  申请人：Berggren Anna

  公开号：US20100280132A1

  公开（公告）日：2010-11-04

  The present invention relates to a method for modifying polyphenol containing plant material(s), wherein said method comprises: mixing at least one polyphenol containing material and at least one solvent to provide a mixture; heating the mixture to eliminate bacterial species present to provide a heated mixture; adding at least one polyphenol modifying strain of lactic acid bacteria and optionally at least one protein source, in optional order or simultaneously, to the heated mixture to provide a fermentation mixture; and subjecting the fermentation mixture to conditions suitable for fermentation of the fermentation mixture to provide a mixture of modified polyphenol containing plant material(s); and optionally eliminating the polyphenol modifying strain of lactic acid bacteria to provide a mixture of modified polyphenol containing plant material(s) free from living lactic acid bacteria.

  本发明涉及一种修改含有多酚的植物材料的方法，其中该方法包括：混合至少一种含有多酚的材料和至少一种溶剂以提供混合物；加热混合物以消除存在的细菌种类，以提供加热混合物；向加热混合物中添加至少一种乳酸菌多酚修饰菌株和可选的至少一种蛋白质源，以任意顺序或同时提供发酵混合物；并将发酵混合物置于适宜的发酵条件下以提供经修改的多酚含量的植物材料的混合物；并可选择性地消除乳酸菌多酚修饰菌株，以提供不含活性乳酸菌的经修改的多酚含量的植物材料混合物。
• METHODS AND COMPOSITIONS FOR IDENTIFYING, PRODUCING AND USING PLANT-DERIVED PRODUCTS FOR MODULATING CELL FUNCTION AND AGING
  申请人：McDaniel David H.

  公开号：US20110159121A1

  公开（公告）日：2011-06-30

  Provided herein are methods of culturing cells in vitro in order to exploit the biochemical production ability of the cells to make metabolites that are evaluated and harvested for their biological effects. Also provided are systems for evaluating extracts from such cultured cells to characterize their biological activity(s), particularly with regard to impact on health, wellbeing, longevity, DNA maintenance, mitochondrial health and/or biogenesis, and so forth. Biologically active extracts, components thereof, and compositions (such as cosmetic or pharmaceutical preparations) made comprising such, are also provided.

  本文提供了在体外培养细胞的方法，以利用细胞的生化生产能力来制造代谢产物，这些代谢产物被评估和收获其生物效应。还提供了用于评估这些培养细胞提取物的系统，以表征其生物活性，特别是对健康、幸福、长寿、DNA维护、线粒体健康和/或生成等方面的影响。还提供了具有生物活性的提取物、其组分以及制成的组合物（如化妆品或制药制剂）。
• METHODS AND COMPOSITIONS FOR ALTERING HEALTH, WELLBEING, AND LIFESPAN
  申请人：McDaniel David H.

  公开号：US20100173024A1

  公开（公告）日：2010-07-08

  Described herein are the results of comprehensive genetic expression and other molecular analysis of the effect of antioxidants on biological systems, including specifically different human cells. Based on these analyses, methods and compositions are described for modifying or influencing the lifespan of cells, tissues, organs, and organisms. In various embodiments, there are provided methods for modulating the activity of the gene maintenance process in order to influence the length and/or structural integrity of the telomere in living cells, as well as methods for modulating the rate/efficiency of the cellular respiration provided by the mitochondria, mitochondrial biogenesis, and maintenance of the mitochondrial membrane potential. Exemplary lifespan altering compounds include natural and synthetic antioxidants, such as plant antioxidant and polyphenol compounds derived from coffee cherry, tea, berry, and so forth, including but not limited to caffeic acid, chlorogenic acid, ferulic acid, quinic acid, proanthocyanidins, ubiquinone, idebenone, or a synthetic form or derivatives thereof.

  本文介绍了抗氧化剂对生物系统的全面基因表达和其他分子分析的结果，包括特定的不同人类细胞。根据这些分析，描述了用于修改或影响细胞、组织、器官和生物体寿命的方法和组合物。在各种实施例中，提供了用于调节基因维护过程活性的方法，以影响活细胞端粒的长度和/或结构完整性，以及调节线粒体提供的细胞呼吸速率/效率、线粒体生物发生和线粒体膜电位维护的方法。示例寿命改变化合物包括天然和合成抗氧化剂，例如从咖啡樱桃、茶、浆果等中提取的植物抗氧化剂和多酚化合物，包括但不限于咖啡酸、绿原酸、阿魏酸、奎尼酸、原花青素、泛醌、伊德贝醌或其合成形式或衍生物。