6²-O-α-maltosylmaltose | 13257-24-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6²-O-α-maltosylmaltose
• 英文别名: 6²-α-maltosylmaltose；maltosyl-α-1,6-maltose；6-O-α-maltosylmaltose；α-D-Glc-(1->4)-α-D-Glc-(1->6)-α-D-Glc-(1->4)-D-Glc；Glc(a1-4)Glc(a1-6)Glc(a1-4)Glc；(2R,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6S)-4,5-dihydroxy-2-(hydroxymethyl)-6-[[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[(2R,3S,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-2-yl]methoxy]oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
• CAS: 13257-24-4
• 化学式: C₂₄H₄₂O₂₁
• 分子量: 666.585
• InChiKey: KLXDQPPPPSDDBD-QVTSYAGHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -9
• 重原子数：
  45
• 可旋转键数：
  10
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  348
• 氢给体数：
  14
• 氢受体数：
  21

反应信息

• 作为反应物：
  描述：

  6²-O-α-maltosylmaltose 在 glucoamylase 作用下， 反应 4.0h， 生成 潘糖 、 葡萄糖
  参考文献：
  名称：

  Transglycosylation properties of maltodextrin glucosidase (MalZ) from Escherichia coli and its application for synthesis of a nigerose-containing oligosaccharide

  摘要：

  The transglycosylation reaction of maltodextrin glucosidase (MalZ) cloned and purified from Escherichia coli K12 was characterized and applied to the synthesis of branched oligosaccharides. Purified MalZ preferentially catalyzed the hydrolysis of maltodextrin, gamma-cyclodextrin (CD), and cycloamylose (CA). In addition, when the enzyme was incubated with 5% maltotriose (G3), a series of transfer products were produced. The resulting major transfer products, annotated as T1, T2, and T3, were purified and their structures were determined by TLC, MALDI-TOF/MS, C-13 NMR, and enzymatic analysis. T1 was identified as a novel compound, maltosyl alpha-1,3-maltose, whereas T2 and T3 were determined to be isopanose and maltosyl-alpha-1,6-maltose, respectively. These results indicated that MalZ transferred sugar moiety mainly to C-3 or C-6-OH of glucose of the acceptor molecule. To obtain highly concentrated transfer products, the enzyme was reacted with 10% liquefied cornstarch, and then glucose and maltose were removed by immobilized yeast. The T1 content of the resulting reaction mixture reached 9.0%. The mixture of T1 containing a nigerose moiety can have an immunopotentiating effect on the human body and may be a potential functional sugar stuff. (C) 2010 Elsevier Inc. All rights reserved.

  DOI：

  10.1016/j.bbrc.2010.05.073
• 作为产物：
  描述：

  麦芽糖 在 acetate buffer 作用下， 反应 30.0h， 生成 6²-O-α-maltosylmaltose
  参考文献：
  名称：

  Iwaki, Keiko; Fuwa, Hidetsugu, Agricultural and Biological Chemistry, 1982, vol. 46, # 9, p. 2233 - 2240

  摘要：

  DOI：

文献信息

• Enzymic syntheses of doubly branched cyclomaltoheptaoses through the reverse action of Pseudomonas isoamylase
  作者：Jun-ichi Abe、Susumu Hizukuri、Kyoko Koizumi、Yoko Kubota、Toshiko Utamura

  DOI：10.1016/0008-6215(88)84060-6

  日期：1988.5

  Abstract Two and three new cyclomaltoheptaose (β-cyclodextrin, cG 7 ) derivatives, respectively, were identified among the products obtained by the action of Pseudomonas isoamylase on maltose and maltotriose, and cG 7 . They were 6 A ,6 D -di- O -α-maltosyl-cG 7 and 6- O -α-(6 2 - O -α-maltosyl)maltosyl-cG 7 , and 6 A ,6 D -di- O -α-maltotriosyl-cG 7 , 6- O -α-(6 3 - O -α-maltotriosyl)maltotriosyl-cG

  摘要在假单胞菌异淀粉酶对麦芽糖和麦芽三糖以及cG 7的作用下，分别鉴定出2个和3个新的环麦芽七糖（β-环糊精，cG 7）衍生物。它们是6 A，6 D -di-O-α-麦芽糖基-cG 7和6- O-α-（6 2-O-α-麦芽糖基）麦芽糖基-cG 7，以及6 A，6 D -di-O -α-麦芽三糖基-cG 7，6-O-α-（6 3 -O-α-麦芽三糖基）麦芽三糖基-cG 7和6-O-α-（6 2-O-α-麦芽三糖基）麦芽三糖基-cG 7 。另外，鉴定出6 1-和6 2-O-α-麦芽糖基麦芽糖是麦芽糖的相互缩合产物。麦芽糖是充当假单胞菌异淀粉酶作用的受体和供体的最小底物。
• Sakano, Yoshiyuki; Sano, Mutsumi; Kobayashi, Tsuneo, Agricultural and Biological Chemistry, 1985, vol. 49, # 12, p. 3391 - 3398
  作者：Sakano, Yoshiyuki、Sano, Mutsumi、Kobayashi, Tsuneo

  DOI：——

  日期：——
• Transglycosylation properties of maltodextrin glucosidase (MalZ) from Escherichia coli and its application for synthesis of a nigerose-containing oligosaccharide
  作者：Kyung-Mo Song、Jae-Hoon Shim、Jong-Tae Park、Sung-Hee Kim、Young-Wan Kim、Winfried Boos、Kwan-Hwa Park

  DOI：10.1016/j.bbrc.2010.05.073

  日期：2010.6

  The transglycosylation reaction of maltodextrin glucosidase (MalZ) cloned and purified from Escherichia coli K12 was characterized and applied to the synthesis of branched oligosaccharides. Purified MalZ preferentially catalyzed the hydrolysis of maltodextrin, gamma-cyclodextrin (CD), and cycloamylose (CA). In addition, when the enzyme was incubated with 5% maltotriose (G3), a series of transfer products were produced. The resulting major transfer products, annotated as T1, T2, and T3, were purified and their structures were determined by TLC, MALDI-TOF/MS, C-13 NMR, and enzymatic analysis. T1 was identified as a novel compound, maltosyl alpha-1,3-maltose, whereas T2 and T3 were determined to be isopanose and maltosyl-alpha-1,6-maltose, respectively. These results indicated that MalZ transferred sugar moiety mainly to C-3 or C-6-OH of glucose of the acceptor molecule. To obtain highly concentrated transfer products, the enzyme was reacted with 10% liquefied cornstarch, and then glucose and maltose were removed by immobilized yeast. The T1 content of the resulting reaction mixture reached 9.0%. The mixture of T1 containing a nigerose moiety can have an immunopotentiating effect on the human body and may be a potential functional sugar stuff. (C) 2010 Elsevier Inc. All rights reserved.
• Iwaki, Keiko; Fuwa, Hidetsugu, Agricultural and Biological Chemistry, 1982, vol. 46, # 9, p. 2233 - 2240
  作者：Iwaki, Keiko、Fuwa, Hidetsugu

  DOI：——

  日期：——