2',5'-bis-O-tert-butyldimethylsilyl-3'-ketouridine | 90813-54-0

分子结构分类

有机化合物 - 有机杂环化合物 - 二嗪类

中文名称

——

中文别名

——

英文名称

2',5'-bis-O-tert-butyldimethylsilyl-3'-ketouridine

英文别名

1-[2',5'-bis-O-(tert-butyldimethylsilyl)-β-D-erythro-pentofuran-3'-ulosyl]uracil；1-[(2R,3S,5R)-3-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-4-oxooxolan-2-yl]pyrimidine-2,4-dione

2',5'-bis-O-tert-butyldimethylsilyl-3'-ketouridine化学式

CAS

90813-54-0

化学式

C₂₁H₃₈N₂O₆Si₂

mdl

——

分子量

470.714

InChiKey

WRUAVYSYUGXTLO-ZTFGCOKTSA-N

BEILSTEIN

——

EINECS

——

物化性质

熔点：

172-173 °C
密度：

1.10±0.1 g/cm3(Predicted)

计算性质

辛醇/水分配系数(LogP)：

3.42
重原子数：

31
可旋转键数：

8
环数：

2.0
sp3杂化的碳原子比例：

0.76
拓扑面积：

94.2
氢给体数：

1
氢受体数：

6

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	2',5'-bis-O-(tert-butyldimethylsilyl)uridine	54925-66-5	C₂₁H₄₀N₂O₆Si₂	472.729
尿嘧啶核苷	uridine	58-96-8	C₉H₁₂N₂O₆	244.204

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	1-[2-O-(tert-butyldimethylsilyl)-β-D-erythro-pentofuran-3-ulosyl]uracil	162611-11-2	C₁₅H₂₄N₂O₆Si	356.451
——	2',5'-bis-O-(tert-butyldimethylsilyl)uridine	54925-66-5	C₂₁H₄₀N₂O₆Si₂	472.729
——	1-(2,5-bis-O-TBDMS-β-D-xylofuranosyl)uracil	90813-55-1	C₂₁H₄₀N₂O₆Si₂	472.729
——	1-<2',5'-bis-O-(tert-butyldimethylsilyl)-3'-C-cyano-3'-deoxy-β-D-xylo-pentofuranosyl>uracil	121055-64-9	C₂₂H₃₉N₃O₅Si₂	481.74
——	2',5'-bis-O-(tert-butyldimethylsilyl)-3'-C-cyano-3'-deoxyuridine	121055-67-2	C₂₂H₃₉N₃O₅Si₂	481.74
——	2',5'-bis-O-(tert-butyldimethylsilyl)-3'-(carboxymethyl)-3'-deoxyuridine	200011-15-0	C₂₃H₄₂N₂O₇Si₂	514.767
——	1-<2,5-bis-O-(tert-butyldimethylsilyl)-3-deoxy-3-methylene-β-D-erythro-pentofuranosyl>uracil	134660-22-3	C₂₂H₄₀N₂O₅Si₂	468.741
——	2',5'-bis-O-(tert-butyldimethylsilyl)-3'-deoxy-3'-[(ethoxycarbonyl)methyl]uridine	178985-82-5	C₂₅H₄₆N₂O₇Si₂	542.82
——	2'-O-(tert-butyldimethylsilyl)-3'-(carboxymethyl)-3'-deoxyuridine	251296-80-7	C₁₇H₂₈N₂O₇Si	400.504
——	2'-O-(tert-butyldimethylsilyl)-3'-hydroxyamino-3'-deoxyuridine	218967-53-4	C₁₅H₂₇N₃O₆Si	373.481
——	(E)-2',5'-bis(O-tert-butyldimethylsilyl)-3'-deoxy-3'-C-(2-hydroxyethylidene)uridine	272780-94-6	C₂₃H₄₂N₂O₆Si₂	498.767
——	1-[(2R,3R,5S)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-4-difluoromethylene-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione	179026-55-2	C₂₂H₃₈F₂N₂O₅Si₂	504.722
——	1-[(2R,3R,4S,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-4-hydroxy-4-(3-hydroxy-propyl)-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione	183987-38-4	C₂₄H₄₆N₂O₇Si₂	530.809
——	1-[(2R,3R,4S,5R)-4-Allyl-3-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-4-hydroxy-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione	183987-31-7	C₂₄H₄₄N₂O₆Si₂	512.794
——	(E)-2',5'-bis(O-tert-butyldimethylsilyl)-3'-deoxy-3'-C-(methoxycarbonylmethylidene)uridine	272780-91-3	C₂₄H₄₂N₂O₇Si₂	526.778
——	1-(2',5'-bis-O-tert-butyldimethylsilyl-3'-C-acetonyl-β-D-xylofuranosyl)uracil	1327159-27-2	C₂₄H₄₄N₂O₇Si₂	528.794
——	5'-amino-2'-O-(tert-butyldimethylsilyl)-3',5'-dideoxy-3'-[(ethoxycarbonyl)methyl]uridine	251296-79-4	C₁₉H₃₃N₃O₆Si	427.573
——	5'-azido-2'-O-(tert-butyldimethylsilyl)-3'-(carboxymethyl)-3',5'-dideoxyuridine	251296-78-3	C₁₇H₂₇N₅O₆Si	425.517
——	1-[2,5-bis(O-tert-butyldimethylsilyl)-3-C-methoxycarbonylmethyl-β-D-xylofuranosyl]uracil	272780-86-6	C₂₄H₄₄N₂O₈Si₂	544.793
——	1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(ethoxycarbonylmethyl)-β-D-xylo-pentofuranosyl]uracil	272780-87-7	C₂₅H₄₆N₂O₈Si₂	558.82
——	5'-azido-2'-O-(tert-butyldimethylsilyl)-3',5'-dideoxy-3'-[(ethoxycarbonyl)methyl]uridine	251296-77-2	C₁₉H₃₁N₅O₆Si	453.571