10,12-Diazahexacyclo[11.11.0.03,11.04,9.015,23.016,21]tetracosa-1(24),2,4,6,8,11,13,15(23),16,18,20-undecaene | 1393093-97-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 10,12-Diazahexacyclo[11.11.0.03,11.04,9.015,23.016,21]tetracosa-1(24),2,4,6,8,11,13,15(23),16,18,20-undecaene
• 英文别名: 10,12-diazahexacyclo[11.11.0.03,11.04,9.015,23.016,21]tetracosa-1(24),2,4,6,8,11,13,15(23),16,18,20-undecaene
• CAS: 1393093-97-4
• 化学式: C₂₂H₁₄N₂
• 分子量: 306.367
• InChiKey: HSNLTOWDIMDVFI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  24
• 可旋转键数：
  0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  28.7
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  3-吲哚甲醛 、 9H-芴-3-胺 在 N-溴代丁二酰亚胺(NBS) 作用下， 反应 9.25h， 以95%的产率得到10,12-Diazahexacyclo[11.11.0.03,11.04,9.015,23.016,21]tetracosa-1(24),2,4,6,8,11,13,15(23),16,18,20-undecaene
  参考文献：
  名称：

  N-Bromosuccinimide as an efficient catalyst for the synthesis of indolo[2,3-b]quinolines

  摘要：

  The use of N-bromosuccinimide as a catalyst promoted the synthesis of polycyclic indolo[2,3-b]quinoline derivatives in good to high yields in the reactions of various aryl amines with indole-3-carbaldehyde at room temperature under mild conditions. (c) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.06.125

文献信息

• N-Bromosuccinimide as an efficient catalyst for the synthesis of indolo[2,3-b]quinolines
  作者：Ramin Ghorbani-Vaghei、Seyedeh Mina Malaekehpoor

  DOI：10.1016/j.tetlet.2012.06.125

  日期：2012.8

  The use of N-bromosuccinimide as a catalyst promoted the synthesis of polycyclic indolo[2,3-b]quinoline derivatives in good to high yields in the reactions of various aryl amines with indole-3-carbaldehyde at room temperature under mild conditions. (c) 2012 Elsevier Ltd. All rights reserved.