5-(4-乙氧基苯基)-5-氧代戊酸 | 34670-10-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 5-(4-乙氧基苯基)-5-氧代戊酸
• 英文名称: 5-(4-ethoxy-phenyl)-5-oxo-valeric acid
• 英文别名: 5-(4-Aethoxy-phenyl)-5-oxo-valeriansaeure；5-(4-Ethoxyphenyl)-5-oxopentanoic acid
• CAS: 34670-10-5
• 化学式: C₁₃H₁₆O₄
• mdl: MFCD02260983
• 分子量: 236.268
• InChiKey: DEARNFFFXXLTCU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.384
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

安全信息

• 海关编码：
  2918990090

反应信息

• 作为反应物：
  描述：

  5-(4-乙氧基苯基)-5-氧代戊酸 在 盐酸 、 amalgamated zinc 、 乙醇 作用下， 生成 5-(4-ethoxy-phenyl)-valeric acid
  参考文献：
  名称：

  Experimental Study of Factors That Affect Thermal Comfort in an Upward-Displacement Air-Conditioned Room

  摘要：

  Experiments were carried out to determine the effect of an underfloor air-conditioning system on comfort. The four factors evaluated were the type of outlet, the distance between the outlet and the occupant, the velocity of the supply air, and the temperature of supply air. It was found that the distance between occupant and outlet has a significant influence on thermal comfort, the velocity and temperature of the supply air have a moderate influence, and the ore of outlet has little influence. Recommended values of these factors were developed that would achieve thermal comfort. The results provide reference data on air distribution in underfloor air-conditioned rooms.

  DOI：

  10.1080/10789669.2002.10391436
• 作为产物：
  描述：

  5-(4-ethoxy-phenyl)-valeric acid 在 sodium dichromate 、 硫酸 、 溶剂黄146 作用下， 生成 5-(4-乙氧基苯基)-5-氧代戊酸
  参考文献：
  名称：

  van der Zanden, Recueil des Travaux Chimiques des Pays-Bas, 1939, vol. 58, p. 181,189

  摘要：

  DOI：

文献信息

• Enantioselective Bromolactonization of Deactivated Olefinic Acids
  作者：Xiaojian Jiang、Shenghui Liu、Si Yang、Mei Jing、Lipeng Xu、Pei Yu、Yuqiang Wang、Ying-Yeung Yeung

  DOI：10.1021/acs.orglett.8b01125

  日期：2018.6.1

  A novel enantioselective bromolactonization of α,β-unsaturated ketones using bifunctional amino-urea catalysts has been developed. The scope of the reaction is evidenced by 23 examples of halolactones bearing various functionalities with up to 99% yield and 99:1 er. Unlike typical urea catalysts that require electron-deficient substituents to enhance the hydrogen bond strength, it is interesting to

  已经开发出使用双官能氨基脲催化剂的α，β-不饱和酮的新型对映选择性溴化。该反应的范围由具有各种官能度的卤代内酯的23个实例证明，产率高达99％，er为99：1 er。与需要缺乏电子的取代基来增强氢键强度的典型尿素催化剂不同，有趣的是，在这种情况下，富含电子的脲对于高对映选择性是必不可少的。此外，实验数据表明，卤代内酯化合物对LPS诱导的RAW 264.7细胞具有相当大的抗炎作用。
• 253. The ω-3-amino-4-methoxy- and -ethoxy-benzoyl derivatives of propionic, butyric, and valeric acid
  作者：S. G. P. Plant、M. E. Tomlinson

  DOI：10.1039/jr9350001092

  日期：——
• Plant; Tomlinson, Journal of the Chemical Society, 1935, p. 856
  作者：Plant、Tomlinson

  DOI：——

  日期：——
• van der Zanden, Recueil des Travaux Chimiques des Pays-Bas, 1939, vol. 58, p. 181,189
  作者：van der Zanden

  DOI：——

  日期：——
• Experimental Study of Factors That Affect Thermal Comfort in an Upward-Displacement Air-Conditioned Room
  作者：Zhiwei Lian、Haiying Wang

  DOI：10.1080/10789669.2002.10391436

  日期：2002.4.1

  Experiments were carried out to determine the effect of an underfloor air-conditioning system on comfort. The four factors evaluated were the type of outlet, the distance between the outlet and the occupant, the velocity of the supply air, and the temperature of supply air. It was found that the distance between occupant and outlet has a significant influence on thermal comfort, the velocity and temperature of the supply air have a moderate influence, and the ore of outlet has little influence. Recommended values of these factors were developed that would achieve thermal comfort. The results provide reference data on air distribution in underfloor air-conditioned rooms.