5-(4-ethoxy-phenyl)-valeraldehyde | 854657-81-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 5-(4-ethoxy-phenyl)-valeraldehyde
• 英文别名: 5-(4-Aethoxy-phenyl)-valeraldehyd；5-(4-Ethoxyphenyl)pentanal
• CAS: 854657-81-1
• 化学式: C₁₃H₁₈O₂
• 分子量: 206.285
• InChiKey: NKKSMYWBEGMFKS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  15
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5-(4-ethoxy-phenyl)-valeraldehyde 生成 5-(4-ethoxy-phenyl)-valeraldehyde-oxime
  参考文献：
  名称：

  Experimental Study of Factors That Affect Thermal Comfort in an Upward-Displacement Air-Conditioned Room

  摘要：

  Experiments were carried out to determine the effect of an underfloor air-conditioning system on comfort. The four factors evaluated were the type of outlet, the distance between the outlet and the occupant, the velocity of the supply air, and the temperature of supply air. It was found that the distance between occupant and outlet has a significant influence on thermal comfort, the velocity and temperature of the supply air have a moderate influence, and the ore of outlet has little influence. Recommended values of these factors were developed that would achieve thermal comfort. The results provide reference data on air distribution in underfloor air-conditioned rooms.

  DOI：

  10.1080/10789669.2002.10391436
• 作为产物：
  描述：

  5-(4-乙氧基苯基)-5-氧代戊酸 在 lead(IV) acetate 、 盐酸 、 amalgamated zinc 、 乙醇 、 硫酸 、 sodium 、 Petroleum ether 、 正丁醇 、 苯 作用下， 生成 5-(4-ethoxy-phenyl)-valeraldehyde
  参考文献：
  名称：

  Experimental Study of Factors That Affect Thermal Comfort in an Upward-Displacement Air-Conditioned Room

  摘要：

  Experiments were carried out to determine the effect of an underfloor air-conditioning system on comfort. The four factors evaluated were the type of outlet, the distance between the outlet and the occupant, the velocity of the supply air, and the temperature of supply air. It was found that the distance between occupant and outlet has a significant influence on thermal comfort, the velocity and temperature of the supply air have a moderate influence, and the ore of outlet has little influence. Recommended values of these factors were developed that would achieve thermal comfort. The results provide reference data on air distribution in underfloor air-conditioned rooms.

  DOI：

  10.1080/10789669.2002.10391436

文献信息

• COMPOUND
  申请人：Kokotos George

  公开号：US20110136879A1

  公开（公告）日：2011-06-09

  The invention provides compounds of formula (I) wherein X is O or S; R 1 is H, OH, SH, nitro, NH 2 , NHC 1-6 alkyl, N(C 1-6 alkyl) 2 , halo, haloC 1-6 alkyl, CN, C 1-6 -alkyl, OC 1-6 alkyl, C 1-6 alkylCOOH, C 1-6 alkylCOOC 1-6 alkyl, C 2-6 -alkenyl, C 3-10 cycloalkyl, C 6-10 aryl, C 1-6 alkylC 6-10 aryl, heterocyclyl, heteroaryl, CONH 2 , CONHC 1-6 alkyl, CON(C 1-6 alkyl) 2 , OCOC 1-6 alkyl, or is an acidic group, such as a group comprising a carboxyl, phosphate, phosphinate, sulfate, sulfonate, or tetrazolyl group; R 2 is as defined for R 1 or R 1 and R 2 taken together can form a 6-membered aromatic ring optionally substituted by up to 4 groups R 5 ; R 3 is H, halo (preferably fluoro), or CHal 3 (preferably CF 3 ), each R 5 is defined as for R 1 ; V 1 is a covalent bond or a C 1-20 alkyl group, or C 2-20 -mono or multiply unsaturated alkenyl group; said alkyl or alkenyl groups being optionally interupted by one or more heteroatoms selected from O, NH, N(C 1-6 alkyl), S, SO, or SO 2 ; M 1 is absent or is a C 5-10 cyclic group or a C 5-15 aromatic group; and R 4 is H, halo, OH, CN, nitro, NH 2 , NHC 1-6 alkyl, N(C 1-6 alkyl) 2 , haloC 1-6 alkyl, a C 1-20 alkyl group, or C 2-20 -mono or multiply unsaturated alkenyl group, said C 1-20 alkyl or C 2-20 alkenyl groups being optionally interupted by one or more heteroatoms selected from O, NH, N(C 1-6 alkyl), S, SO, or SO 2 ; with the proviso that the group V 1 M 1 R 4 as a whole provides at least 4 backbone atoms from the C(R 3 ) group; or a salt, ester, solvate, N-oxide, or prodrug thereof; for use in the treatment of a chronic inflammatory condition.
• US9597318B2
  申请人：——

  公开号：US9597318B2

  公开（公告）日：2017-03-21