4-methoxy-cinnamic acid diethylamide | 23784-83-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: 4-methoxy-cinnamic acid diethylamide
• 英文别名: 4-Methoxy-N.N-diaethyl-cinnamamid；4-Methoxy-zimtsaeure-diaethylamid；4-Methoxy-zimtsaeure-N,N-diethylamid；N,N-diethyl-3-(4-methoxyphenyl)prop-2-enamide
• CAS: 23784-83-0
• 化学式: C₁₄H₁₉NO₂
• 分子量: 233.31
• InChiKey: ALPSZSGLINZWDO-UHFFFAOYSA-N

物化性质

• 沸点：
  410.6±28.0 °C(Predicted)
• 密度：
  1.037±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-methoxy-cinnamic acid diethylamide 在 碘苯二乙酸 、 硫酸 、 三氟化硼乙醚 作用下， 以 二氯甲烷 为溶剂， 以70%的产率得到N,N-diethyl-2-(4-methoxyphenyl)-2-oxoacetamide
  参考文献：
  名称：

  无金属的串联氧化芳基迁移和C–C键裂解：由丙烯酸衍生物合成α-酮酰胺和酯

  摘要：

  已经发现了一种由高价碘试剂介导的新型无金属串联氧化芳基迁移/ CC键断裂反应。所提出的转变通过伴随CC键断裂的1，2-芳基转移的协同过程，使人们容易地从丙烯酸衍生物中直接获得重要的α-酮酰胺和α-酮酸酯衍生物。

  DOI：

  10.1021/ol502834g
• 作为产物：
  描述：

  二乙胺 、 p-methoxycinnamoyl chloride 在 三乙胺 作用下， 以 乙醚 为溶剂， 反应 1.0h， 以67%的产率得到4-methoxy-cinnamic acid diethylamide
  参考文献：
  名称：

  안료 분산액 및 그것을 사용한 감광성 수지 조성물의 제조 방법

  摘要：

  The dispersibility of the pigment after a period of time is good, and a photosensitive resin composition capable of forming fine patterns with low exposure doses and high resolution can be provided with a pigment dispersion liquid that can be applied even after a period of time, and a method for manufacturing a photosensitive resin composition using the pigment dispersion liquid. The pigment dispersion liquid related to the present invention contains a pigment, a solvent, and a compound represented by formula (1). In the formula, R1 and R2 independently represent a hydrogen atom or an organic group, but at least one of them represents an organic group. R1 and R2 may form a cyclic structure by bonding, and may include a bond of a hetero atom. R3 represents a single bond or an organic group. R4 to R9 independently represent a hydrogen atom, an organic group, etc., but R6 and R7 do not become hydroxy groups. R10 represents a hydrogen atom or an organic group.

  公开号：

  KR102140676B1

文献信息

• Catalytic Asymmetric Direct-Type 1,4-Addition Reactions of Alkanesulfonamides
  作者：Shū Kobayashi、Yasuhiro Yamashita、Ryo Igarashi、Hirotsugu Suzuki

  DOI：10.1055/s-0036-1588737

  日期：2017.7

  4-addition reactions of alkanesulfonamides were developed on the ‘product base’ strategy. Alkanesulfonamides reacted with α,β-unsaturated amides in good to high yields with good to high diastereo- and enantioselectivities using a chiral alkaline metal amide. To our knowledge, this is the first example of a catalytic asymmetric C–C bond-forming reaction using an alkanesulfonamide without any activating group

  链烷磺酰胺的催化不对称 1,4-加成反应是基于“产品基础”策略开发的。使用手性碱金属酰胺，链烷磺酰胺与 α,β-不饱和酰胺以良好至高产率以及良好至高的非对映选择性和对映选择性反应。据我们所知，这是使用烷烃磺酰胺在其 α 位没有任何活化基团的催化不对称 C-C 键形成反应的第一个例子。
• N,N-Dialkyl-β-hydroxyamides via the Reformatsky Reaction^1,2
  作者：Nathan L. Drake、Charles M. Eaker、Wilbur Shenk

  DOI：10.1021/ja01182a073

  日期：1948.2
• NOVEL BASE GENERATOR AND ADHESION ENHANCER
  申请人：Tokyo Ohka Kogyo Co., Ltd.

  公开号：EP2725011B1

  公开（公告）日：2021-10-27
• Metal-Free Tandem Oxidative Aryl Migration and C–C Bond Cleavage: Synthesis of α-Ketoamides and Esters from Acrylic Derivatives
  作者：Le Liu、Liang Du、Daisy Zhang-Negrerie、Yunfei Du、Kang Zhao

  DOI：10.1021/ol502834g

  日期：2014.11.7

  novel tandem metal-free oxidative aryl migration/C–C bond-cleavage reaction, mediated by hypervalent iodine reagent, has been discovered. The presented transformation provided straightforward access to important α-ketoamide and α-ketoester derivatives from readily available acrylic derivatives via a concerted process of 1,2-aryl shift concomitant with C–C bond cleavage.

  已经发现了一种由高价碘试剂介导的新型无金属串联氧化芳基迁移/ CC键断裂反应。所提出的转变通过伴随CC键断裂的1，2-芳基转移的协同过程，使人们容易地从丙烯酸衍生物中直接获得重要的α-酮酰胺和α-酮酸酯衍生物。
• 안료 분산액 및 그것을 사용한 감광성 수지 조성물의 제조 방법
  申请人：TOKYO OHKA KOGYO CO., LTD. 도쿄 오카 고교 가부시키가이샤(519980627398)

  公开号：KR102140676B1

  公开（公告）日：2020-08-04

  [과제]시간 경과 후의 안료의 분산성이 양호하고, 저노광량으로 고밀착성인 미소 패턴을 형성 가능한 감광성 수지 조성물을 시간 경과 후에도 부여할 수 있는 안료 분산액 및 그것을 사용한 감광성 수지 조성물의 제조 방법을 제공한다. [해결 수단]본 발명과 관련된 안료 분산액은 안료와, 용제와, 하기 식(1)로 나타내는 화합물을 함유한다. 식 중, R1 및 R2는 각각 독립적으로 수소 원자 또는 유기기를 나타내지만, 적어도 한쪽은 유기기를 나타낸다. R1 및 R2는 이들이 결합해 환상 구조를 형성하고 있어도 되고, 헤테로 원자의 결합을 포함하고 있어도 된다. R3은 단결합 또는 유기기를 나타낸다. R4~R9는 각각 독립적으로 수소 원자, 유기기 등을 나타내지만, R6 및 R7이 수산기가 되는 경우는 없다. R10은 수소 원자 또는 유기기를 나타낸다.

  The dispersibility of the pigment after a period of time is good, and a photosensitive resin composition capable of forming fine patterns with low exposure doses and high resolution can be provided with a pigment dispersion liquid that can be applied even after a period of time, and a method for manufacturing a photosensitive resin composition using the pigment dispersion liquid. The pigment dispersion liquid related to the present invention contains a pigment, a solvent, and a compound represented by formula (1). In the formula, R1 and R2 independently represent a hydrogen atom or an organic group, but at least one of them represents an organic group. R1 and R2 may form a cyclic structure by bonding, and may include a bond of a hetero atom. R3 represents a single bond or an organic group. R4 to R9 independently represent a hydrogen atom, an organic group, etc., but R6 and R7 do not become hydroxy groups. R10 represents a hydrogen atom or an organic group.