2,5-dimethyl-1,6-hexanedial | 67101-64-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,5-dimethyl-1,6-hexanedial
• 英文别名: 2,5-dimethyl-hexanedial；2,5-Dimethylhexanedial
• CAS: 67101-64-8
• 化学式: C₈H₁₄O₂
• 分子量: 142.198
• InChiKey: FCLIOENZNRDDCH-UHFFFAOYSA-N

物化性质

• 沸点：
  209.8±23.0 °C(Predicted)
• 密度：
  0.911±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,5-dimethyl-1,6-hexanedial 在 silver(l) oxide 作用下， 生成 2,5-二甲基己二酸
  参考文献：
  名称：

  Sa-Le-Thi-Thuan; Wiemann,J., Bulletin de la Societe Chimique de France, 1968, p. 4622 - 4631

  摘要：

  DOI：
• 作为产物：
  描述：

  1,5-已二烯 、 一氧化碳 在 acetylacetonatodicarbonylrhodium(l) 氢气 、 三[3,4-双(三氟甲基)苯基]膦 作用下， 以 二氧化碳 为溶剂， 60.0 ℃ 、4.0 MPa 条件下， 反应 2.0h， 生成 辛二醛 、 2-甲基-5-己烯-1-醛 、 2,5-dimethyl-1,6-hexanedial 、 2-methyl-1,7-heptanedial
  参考文献：
  名称：

  Rhodium–tris(3,5-bis(trifluoromethyl)phenyl)phosphine catalyzed hydroformylation of dienes to dialdehydes in supercritical carbon dioxide with high activity

  摘要：

  Rhodium-catalyzed hydroformylation of 1,5-hexadiene and 1,7-octadiene to corresponding dialdehydes was investigated in compressed CO2 and in toluene using different fluorinated phosphine compounds as ligands. A rhodium complex using tris(3,5-bis(trifluoromethyl)phenyl)phosphine is highly effective in compressed CO2 for double hydroformylation of 1,5-hexadiene, whose TOF value is much larger than those reported so far. It has been shown that this ligand is effective also for the hydroformylation of 1,7-octadiene and scCO(2) is a better solvent than a conventional organic solvent of toluene for the title reaction. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2003.10.219

文献信息

• 1,5-Hexadiene selective hydroformylation reaction catalyzed with Rh(acac){P(OPh)3}2/P(OPh)3 and Rh(acac)(CO)(PPh3) / PPh3 complexes
  作者：A.M. Trzeciak、J.J. Ziółkowski

  DOI：10.1016/0022-328x(94)87017-9

  日期：1994.1

  Hydroformylation of 1,5-hexadiene, catalyzed by the system Rh(acac)P(OPh)(3)}(2)/P(OPh)(3) (I), leads to the formation of mono- and dialdehydes, 4-heptenal, 2-Me-3-hexenal and octane-1,8-dial, 2,5-Me(2)-hexanedial respectively. The yield of dialdehydes increases with temperature and pressure and reaches 100% at 80 degrees C and 10 atm of CO/H-2=1. The reaction catalyzed by Rh(acac)(Co)(PPh(3))/PPh(3) (II) system produces, besides dialdehydes, monoaldehydes with a terminal double bond, namely 6-heptenal and 2-Me-5-hexenal. The migration of the double bonds in monoaldehydes depends mainly on the donor properties of modifying ligands. Phosphine when used as a modifying ligand (II), because of its strong donor properties, restricts isomerization (double bond migration) and diminishes yield of 4-heptenal. In contrast, when less strongly donating ligands such as phosphites are used as modifying ligands (I), independently of its steric properties, 4-heptenal is the main reaction product.
• JPS61238751A
  申请人：——

  公开号：JPS61238751A

  公开（公告）日：1986-10-24
• ABSORBENT ARTICLES CAPABLE OF INDICATING THE PRESENCE OF URINARY TRACT INFECTIONS
  申请人：SONG XUEDONG

  公开号：US20100290948A1

  公开（公告）日：2010-11-18

  In accordance with one embodiment of the present disclosure, a diagnostic test kit for detecting the presence or absence of nitrites within a test sample is disclosed. The test kit comprises an aromatic primary amine that is capable of reacting with a nitrite to form a diazonium ion. The test kit also comprises a lateral flow device that comprises a chromatographic medium and an absorbent material that receives the test sample after flowing through the chromatographic medium. The chromatographic medium defines a detection zone within which is contained a detection reagent consisting of a nucleophilic aromatic amine that is directly bound through covalent bonding to the chromatographic medium. The detection reagent is capable of reacting with the diazonium ion to form an indicator (e.g., azo compound). The indicator exhibits a color that is different than the color of the detection reagent.
• PRODUCTION METHOD FOR IMMOBILIZED MICROORGANISMS AND PRODUCTION METHOD FOR AMINO ACID USING THE SAME
  申请人：KANEKA CORPORATION

  公开号：US20220025351A1

  公开（公告）日：2022-01-27

  An object of the present invention is to provide a method for producing an immobilized microorganism having high filtration properties, and to provide a method for producing an amino acid using the immobilized microorganism. A method for producing an immobilized microorganism is characterized in that a microorganism is contacted with carboxymethyl cellulose sodium salt and then contacted with polyethylenimine and an alkane dial after the first contact with carboxymethyl cellulose sodium salt.
• US4131623A
  申请人：——

  公开号：US4131623A

  公开（公告）日：1978-12-26