2,2'-((2-((2-hydroxyethoxy)methyl)-2-methylpropane-1,3-diyl)bis(oxy))diethanol | 166195-01-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,2'-((2-((2-hydroxyethoxy)methyl)-2-methylpropane-1,3-diyl)bis(oxy))diethanol
• 英文别名: 1,1,1-Tris(hydroxyethoxymethyl)ethane；2-[3-(2-hydroxyethoxy)-2-(2-hydroxyethoxymethyl)-2-methylpropoxy]ethanol
• CAS: 166195-01-3
• 化学式: C₁₁H₂₄O₆
• 分子量: 252.308
• InChiKey: LTGHXQGVWOHRIC-UHFFFAOYSA-N

物化性质

• 沸点：
  398.3±42.0 °C(Predicted)
• 密度：
  1.137±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.6
• 重原子数：
  17
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  88.4
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2,2'-((2-((2-hydroxyethoxy)methyl)-2-methylpropane-1,3-diyl)bis(oxy))diethanol 在 吡啶 、 氯化亚砜 作用下， 以 二氯甲烷 为溶剂， 生成 1,3-bis(2-chloroethoxy)-2-(2-chloroethoxymethyl)-2-methylpropane
  参考文献：
  名称：

  Mills, Jerry L.; Harwell, David E.; Marquis, Virginia K. De, Phosphorus, Sulfur and Silicon and the Related Elements, 1994, vol. 87, # 1-4, p. 149 - 156

  摘要：

  DOI：
• 作为产物：
  描述：

  1,1,1-三(羟甲基)乙烷 在 sodium hydride 、 臭氧 作用下， 以 甲醇 、 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 生成 2,2'-((2-((2-hydroxyethoxy)methyl)-2-methylpropane-1,3-diyl)bis(oxy))diethanol
  参考文献：
  名称：

  Biomimetic ferrichrome: structural motifs for switching between narrow- and broad-spectrum activities in P. putida and E. coli

  摘要：

  具有铁铬样活性的模拟物使得可以制定广谱活性化合物的指导方针。偏离这些指导方针会提供窄谱活性化合物。

  DOI：

  10.1039/c5dt02685g

文献信息

• Functionalized aza-crytand ligands for diagnostic imaging applications
  申请人：Mallinckrodt Medical, Inc.

  公开号：US05417959A1

  公开（公告）日：1995-05-23

  The present invention provides new and structurally diverse compositions comprising compounds of the general formula: ##STR1## Wherein V is CR.sub.1 or N; W is CR.sub.2 or N; R.sub.1 and R.sub.2 may be the same or different and are hydrogen, C.sub.1 -C.sub.8 alkyl, or C.sub.6 -C.sub.10 aryl, optionally R.sub.1 and R.sub.2 may be substituted by one or more hydroxy, C.sub.1 -C.sub.8 alkyl, C.sub.1 -C.sub.8 hydroxyalkyl, C.sub.1 -C.sub.8 alkoxy, C.sub.6 -C.sub.10 aryl, C.sub.6 -C.sub.10 hydroxyaryl, C.sub.6 -C.sub.10 aryloxy, --CO.sub.2 R.sub.3, CONR.sub.4 R.sub.5, or --NR.sub.4 R.sub.5 ; X and Y may be the same or different and the O, NR.sub.6, S, or CR.sub.7 R.sub.8 ; R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 may be the same or different and are hydrogen, C.sub.1 -C.sub.8 alkyl, C.sub.1 -C.sub.8 hydroxyalkyl, or C.sub.1 -C.sub.8 alkoxyalkyl; R.sub.4 and R.sub.5 may form a 5 or 6 membered carbocyclic ring optionally containing singularly or in combination nitrogen, oxygen or sulfur; a, b, c, d and e may be same or different and are zero to about 10; and Z is --CO.sub.2 H, --PO.sub.3 H.sub.2, --SO.sub.3 H, or --CONHOH. Methods for imaging using compositions of the invention as diagnostic imaging agents are also provided.

  本发明提供了新的结构多样的化合物组成物，包括一般式的化合物：##STR1## 其中，V为CR.sub.1或N; W为CR.sub.2或N; R.sub.1和R.sub.2可以相同也可以不同，分别为氢、C.sub.1-C.sub.8烷基或C.sub.6-C.sub.10芳基，可选择性地，R.sub.1和R.sub.2可以被一个或多个羟基、C.sub.1-C.sub.8烷基、C.sub.1-C.sub.8羟基烷基、C.sub.1-C.sub.8烷氧基、C.sub.6-C.sub.10芳基、C.sub.6-C.sub.10羟基芳基、C.sub.6-C.sub.10芳氧基、--CO.sub.2R.sub.3、CONR.sub.4R.sub.5或--NR.sub.4R.sub.5置换；X和Y可以相同也可以不同，分别为O、NR.sub.6、S或CR.sub.7R.sub.8；R.sub.3、R.sub.4、R.sub.5、R.sub.6、R.sub.7和R.sub.8可以相同也可以不同，分别为氢、C.sub.1-C.sub.8烷基、C.sub.1-C.sub.8羟基烷基或C.sub.1-C.sub.8烷氧基烷基；R.sub.4和R.sub.5可以形成一个含有氮、氧或硫的5或6元环烃环；a、b、c、d和e可以相同也可以不同，分别为0到大约10；Z为--CO.sub.2H、--PO.sub.3H.sub.2、--SO.sub.3H或--CONHOH。本发明还提供了使用该组成物作为诊断成像剂的成像方法。
• Apparatus for producing a curable polyurethane froth
  申请人：UNION CARBIDE CORPORATION

  公开号：EP0070324A1

  公开（公告）日：1983-01-26

  Described herein is an apparatus for the continuous production of a curable polyurethane froth which apparatus comprises separate sources of a polyol, an isocyanate, a catalyst and an inert gas, means including separate conduits for feeding said polyol, isocyanate and inert gas separately and under pressure at controlled flow rates from said sources to a mixing device containing inlet openings to receive said polyol, isocyanate and inert gas, means for mixing said polyol, isocyanate and inert gas to produce a froth, and an outlet opening for the resulting froth, means for delivering the froth from said mixing device to a second mixing device, a conduit for feeding the catalyst under pressure at a controlled flow rate to the second mixing device, and means for mixing the froth and catalyst, said mixing device containing inlet openings to receive the froth and catalyst and an outlet opening for the resulting catalyzed froth and means for delivering the catalyzed froth from the mixing device onto a substrate.

  本发明描述了一种连续生产可固化聚氨酯泡沫的设备，该设备包括多元醇、异氰酸酯、催化剂和惰性气体的单独来源；包括单独导管的装置，用于将所述多元醇、异氰酸酯和惰性气体分别以受控流速在压力下从所述来源输送至混合装置，该混合装置包含用于接收所述多元醇、异氰酸酯和惰性气体的入口；用于将所述多元醇、异氰酸酯和惰性气体混合以产生泡沫的装置；用于将泡沫从所述混合装置输送至第二混合装置的装置；用于将催化剂以受控流速在压力下输送至第二混合装置的导管；用于将催化剂以受控流速在压力下输送至第二混合装置的装置、将沫子从上述混合装置输送到第二混合装置的装置，将催化剂在压力下以可控流速输送到第二混合装置的导管，以及将沫子和催化剂混合的装置，上述混合装置包含接收沫子和催化剂的入口和产生的催化沫子的出口，以及将催化沫子从混合装置输送到基质上的装置。
• A frothable polyurethane composition and a cellular foam produced therefrom
  申请人：UNION CARBIDE CORPORATION

  公开号：EP0069163A1

  公开（公告）日：1983-01-12

  Described herein is a frothable thermosetting polyurethane-forming composition, a process for producing a curable froth from said composition, a process for applying the curable froth to a substrate and a cured cellular polyurethane produced from the curable froth.

  本文描述了一种可起泡的热固性聚氨酯成型组合物、一种用所述组合物生产可固化泡沫的工艺、一种将可固化泡沫应用于基材的工艺以及一种用可固化泡沫生产的固化蜂窝状聚氨酯。
• One-component polyurethane adhesive compositions
  申请人：AMERICAN CYANAMID COMPANY

  公开号：EP0124753A2

  公开（公告）日：1984-11-14

  A heat-curable polyurethane composition, comprising: (a) a secondary or tertiary aliphatic diisocyanate; (b) a hydroxyl compound; and (c) a curingly effective amount of a catalyst selected from the group consisting of magnesium acetylacetonate, nickel acetylacetonate, magnesium stearate, cadmium stearate, and organic acid salts of 1,8-diazabicyclo [5.4.0] undec-7- ene.

  一种热固化聚氨酯组合物，包括 (a) 仲或叔脂肪族二异氰酸酯； (b) 羟基化合物；和 (c) 固化有效量的催化剂，该催化剂选自乙酰丙酮镁、乙酰丙酮镍、硬脂酸 镁、硬脂酸镉和 1，8-二氮杂双环[5.4.0]十一-7-烯的有机酸盐组成的组。
• Storage stable, one package, heat curable poly urea/urethane coating compositions
  申请人：AMERICAN CYANAMID COMPANY

  公开号：EP0150330A2

  公开（公告）日：1985-08-07

  New and improved storage stable, one package, heat-curable poly urea/urethane coating compositions are disclosed which comprise: (a) a mixture or prepolymer of (i) a poly aliphatic isocyanate compound of the formula: wherein R and R' are each, independently, hydrogen, alkyl or substituted alkyl and X is a bridging means selected from divalent aliphatic, cycloaliphatic, or aromatic groups, or a polymeric adduct of said aliphatic isocyanate compound possessing poly aliphatic isocyanate functionality; and (ii) an approximately stoichiometric amount of at least one monomeric or polymeric compound containing a plurality of isocyanate reactive hydrogens; and (b) a minor effective amount of a polymerization calalyst. The compositions cure when heated to above about 100°C to form coatings which exhibit good abrasion resistance, solvent resistance, weather resistance and good adhesion to a wide variety of substrates. The coating compositions are stable upon storage for several months and have useful coating lives in the presence of atmospheric moisture of up to several days. In a preferred embodiment the new and improved poly urea/urethane coating compositions comprises a prepolymer solution containing a prepolymer derived from a,a,a',a'-tetramethylxylyene diisocyanate and 9-amino-10-hydroxystearylamine having a solids content of from about 30% by weight to about 80% by weight and an isocyanate content of from about 2% by weight to about 10% by weight, based on the total weight of the solution, and a minor effective amount of a dibutyltin dilaurate catalyst.

  本发明公开了新型和改进的贮存稳定、单包装、热固化聚脲/聚氨酯涂料组合物，其中包括 (a) 以下物质的混合物或预聚物 (i) 式中的多脂肪族异氰酸酯化合物： 其中 R 和 R'各自独立地是氢、烷基或取代烷基，X 是选自二价脂肪族、环脂族或芳香族基团的桥接手段，或具有多脂 族异氰酸酯官能团的所述脂肪族异氰酸酯化合物的聚合物加合物；和 (ii) 约为等当量的含有多个异氰酸酯活性氢的至少一种单体或聚合化合物； 以及 (b) 少量有效的聚合催化剂。 这些组合物在加热至约 100°C 以上时固化，形成具有良好耐磨性、耐溶剂性、耐候性和与各种基材良好粘附性的涂层。涂层组合物在储存数月后保持稳定，在大气湿度存在的情况下，涂层寿命可达数天。 在一个优选的实施方案中，新型改进的聚脲/聚氨酯涂料组合物包括一种预聚物溶液，其中含有一种由 a、a、a'、a'-四甲基乙烯二异氰酸酯和 9-氨基-10-羟基硬脂酰胺的预聚物，其固体含量为约 30%（重量）至约 80%（重量），异氰酸酯含量为约 2%（重量）至约 10%（重量）（基于溶液总重量），以及少量有效的二月桂酸二丁基锡催化剂。