1-[3-(phenylsulfanyl)phenyl]-1H-imidazole | 1520092-59-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-[3-(phenylsulfanyl)phenyl]-1H-imidazole
• 英文别名: 1-(3-Phenylsulfanylphenyl)imidazole；1-(3-phenylsulfanylphenyl)imidazole
• CAS: 1520092-59-4
• 化学式: C₁₅H₁₂N₂S
• 分子量: 252.34
• InChiKey: CSGDPYPYKTZIMN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  43.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  咪唑 、 3-iodophenyl phenyl sulfide 在 copper(l) iodide 、 1-(2-hydroxyphenyl)-3-dimethylaminoprop-2-enone 、 caesium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 12.0h， 以81%的产率得到1-[3-(phenylsulfanyl)phenyl]-1H-imidazole
  参考文献：
  名称：

  Copper-Catalyzed Selective Single Arylsulfanylation of Aryl Diiodides with Aryl Thiols

  摘要：

  Selective single arylsulfanylation reactions of aryl diiodides with aryl or hetaryl thiols to give a broad array of iodine-functionalized sulfides were developed. Further elaboration of the iodine-containing products to provide a variety of aryl and hetaryl sulfides through coupling reactions was also demonstrated.

  DOI：

  10.1055/s-0033-1338525

文献信息

• Copper-Catalyzed Selective Single Arylsulfanylation of Aryl Diiodides with Aryl Thiols
  作者：Jie-Ping Wan、Yunyun Liu、Hang Wang、Xiaoji Cao、Zheng Fang

  DOI：10.1055/s-0033-1338525

  日期：——

  Selective single arylsulfanylation reactions of aryl diiodides with aryl or hetaryl thiols to give a broad array of iodine-functionalized sulfides were developed. Further elaboration of the iodine-containing products to provide a variety of aryl and hetaryl sulfides through coupling reactions was also demonstrated.