13-cyclohexyl-10-[(1,1-dimethylethoxy)carbonyl]-3-methoxy-beta-oxo-7H-indolo[2,1-a][2]benzazepine-6-propanoic acid ethyl ester | 1127234-87-0

分子结构分类

有机化合物 - 有机杂环化合物 - 吲哚及其衍生物

中文名称

——

中文别名

——

英文名称

13-cyclohexyl-10-[(1,1-dimethylethoxy)carbonyl]-3-methoxy-beta-oxo-7H-indolo[2,1-a][2]benzazepine-6-propanoic acid ethyl ester

英文别名

tert-butyl 13-cyclohexyl-6-(3-ethoxy-3-oxopropanoyl)-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylate

13-cyclohexyl-10-[(1,1-dimethylethoxy)carbonyl]-3-methoxy-beta-oxo-7H-indolo[2,1-a][2]benzazepine-6-propanoic acid ethyl ester化学式

CAS

1127234-87-0

化学式

C₃₄H₃₉NO₆

mdl

——

分子量

557.687

InChiKey

HEGHQTWUFVMQNQ-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

7.3
重原子数：

41
可旋转键数：

10
环数：

5.0
sp3杂化的碳原子比例：

0.44
拓扑面积：

83.8
氢给体数：

0
氢受体数：

6

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	tert-butyl 6-acetyl-13-cyclohexyl-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylate	1127234-86-9	C₃₁H₃₅NO₄	485.623

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	tert-butyl 13-cyclohexyl-6-(2-(ethoxycarbonyl)-4-methyl-2-pentenoyl)-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylate	——	C₃₈H₄₅NO₆	611.778
——	tert-butyl 13-cyclohexyl-6-((2E,Z)-3-(dimethylamino)-2-(ethoxycarbonyl)-2-propenoyl)-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylate	1127234-89-2	C₃₇H₄₄N₂O₆	612.766
——	13-cyclohexyl-6-[3-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-1,3-dioxopropyl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid 1,1-dimethylethyl ester	1127238-15-6	C₃₈H₄₆N₂O₆	626.793
——	13-cyclohexyl-6-[(2E,Z)-3-(dimethylamino)-2-[[(2R,6S)-2,6-dimethyl-4-morpholinyl]carbonyl]-1-oxo-2-propenyl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid 1,1-dimethylethyl ester	1127238-16-7	C₄₁H₅₁N₃O₆	681.872
——	13-cyclohexyl-6-[(2E,Z)-3-(dimethylamino)-2-[[(2R,6S)-2,6-dimethyl-4-morpholinyl]carbonyl]-1-oxo-2-propenyl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid	1127238-17-8	C₃₇H₄₃N₃O₆	625.765
——	13-cyclohexyl-6-[(2E,Z)-3-(dimethylamino)-2-[[(2R,6S)-2,6-dimethyl-4-morpholinyl]carbonyl]-1-oxo-2-propenyl]-3-methoxy-N-[(1-methylethyl)sulfonyl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide	1127238-19-0	C₄₀H₅₀N₄O₇S	730.926
——	13-cyclohexyl-6-[1-cyclopropyl-4-(ethoxycarbonyl)-1H-pyrazol-3-yl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid 1,1-dimethylethyl ester	1195781-75-9	C₃₈H₄₃N₃O₅	621.777
——	13-cyclohexyl-6-[1-cyclopropyl-4-(ethoxycarbonyl)-1H-pyrazol-3-yl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid	1195781-83-9	C₃₄H₃₅N₃O₅	565.669
——	6-[1-cyclobutyl-4-(ethoxycarbonyl)-1H-pyrazol-5-yl]-13-cyclohexyl-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid 1,1-dimethylethyl ester	1195778-70-1	C₃₉H₄₅N₃O₅	635.803
——	13-cyclohexyl-6-[4-(ethoxycarbonyl)-1-(1-methyl-4-piperidinyl)-1H-pyrazol-5-yl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid 1,1-dimethylethyl ester	1195781-03-3	C₄₁H₅₀N₄O₅	678.872
——	13-cyclohexyl-6-[4-(ethoxycarbonyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-5-yl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid 1,1-dimethylethyl ester	1195778-31-4	C₄₀H₄₇N₃O₆	665.83
——	13-cyclohexyl-6-[1-cyclopropyl-4-(ethoxycarbonyl)-1H-pyrazol-5-yl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid	1195781-78-2	C₃₄H₃₅N₃O₅	565.669
——	6-[1-cyclobutyl-4-(ethoxycarbonyl)-1H-pyrazol-5-yl]-13-cyclohexyl-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid	1195781-72-6	C₃₅H₃₇N₃O₅	579.696
——	13-cyclohexyl-6-[4-(ethoxycarbonyl)-1-(3-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid 1,1-dimethylethyl ester	1195778-00-7	C₄₁H₄₄N₄O₅	672.824
——	13-cyclohexyl-6-[4-(ethoxycarbonyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-5-yl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid	1195778-33-6	C₃₆H₃₉N₃O₆	609.722
——	tert-butyl 13-cyclohexyl-6-(1-cyclopropyl-4-(ethoxycarbonyl)-3-isopropyl-1H-pyrazol-5-yl)-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylate	1195781-97-5	C₄₁H₄₉N₃O₅	663.857
——	13-cyclohexyl-6-[1-cyclopropyl-4-(4-morpholinylcarbonyl)-1H-pyrazol-3-yl]-3-methoxy-N-[(1-methylethyl)sulfonyl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide	1195779-44-2	C₃₉H₄₅N₅O₆S	711.882
——	1-cyclobutyl-5-[13-cyclohexyl-3-methoxy-10-[[[(1-methylethyl)sulfonyl]amino]carbonyl]-7H-indolo[2,1-a][2]benzazepin-6-yl]-1H-pyrazole-4-carboxylic acid	1195778-76-7	C₃₆H₄₀N₄O₆S	656.803
——	1-cyclobutyl-5-[13-cyclohexyl-3-methoxy-10-[[[(1-methylethyl)sulfonyl]amino]carbonyl]-7H-indolo[2,1-a][2]benzazepin-6-yl]-1H-pyrazole-4-carboxylic acid ethyl ester	1195780-98-3	C₃₈H₄₄N₄O₆S	684.857
——	1-cyclobutyl-5-[13-cyclohexyl-3-methoxy-10-[[[(2-methylpropyl)sulfonyl]amino]carbonyl]-7H-indolo[2,1-a][2]benzazepin-6-yl]-1H-pyrazole-4-carboxylic acid	1195778-74-5	C₃₇H₄₂N₄O₆S	670.83
——	1-cyclobutyl-5-[13-cyclohexyl-3-methoxy-10-[[[(2-methylpropyl)sulfonyl]amino]carbonyl]-7H-indolo[2,1-a][2]benzazepin-6-yl]-1H-pyrazole-4-carboxylic acid ethyl ester	1195778-72-3	C₃₉H₄₆N₄O₆S	698.883
——	5-[13-cyclohexyl-3-methoxy-10-[[[(1-methylethyl)sulfonyl]amino]carbonyl]-7H-indolo[2,1-a][2]benzazepin-6-yl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxylic acid	1195781-12-4	C₃₇H₄₂N₄O₇S	686.829
——	5-[13-cyclohexyl-3-methoxy-10-[[[(1-methylethyl)sulfonyl]amino]carbonyl]-7H-indolo[2,1-a][2]benzazepin-6-yl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxylic acid ethyl ester	1195781-10-2	C₃₉H₄₆N₄O₇S	714.883
——	13-cyclohexyl-6-[1-cyclopropyl-4-(4-morpholinylcarbonyl)-1H-pyrazol-5-yl]-3-methoxy-N-[(1-methylethyl)sulfonyl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide	1127238-75-8	C₃₉H₄₅N₅O₆S	711.882
——	13-cyclohexyl-6-(1-cyclopropyl-4-(ethoxycarbonyl)-3-isopropyl-1H-pyrazol-5-yl)-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid	1195782-68-3	C₃₇H₄₁N₃O₅	607.75
——	5-[13-cyclohexyl-3-methoxy-10-[[[(2-methylpropyl)sulfonyl]amino]carbonyl]-7H-indolo[2,1-a][2]benzazepin-6-yl]-1'-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxylic acid	1195778-37-0	C₃₈H₄₄N₄O₇S	700.856
——	5-[13-cyclohexyl-3-methoxy-10-[[[(2-methylpropyl)sulfonyl]amino]carbonyl]-7H-indolo[2,1-a][2]benzazepin-6-yl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxylic acid ethyl ester	1195778-35-8	C₄₀H₄₈N₄O₇S	728.91
——	6-[1-cyclobutyl-4-(4-morpholinylcarbonyl)-1H-pyrazol-5-yl]-13-cyclohexyl-3-methoxy-N-[(1-methylethyl)sulfonyl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide	1195779-25-9	C₄₀H₄₇N₅O₆S	725.909
——	6-[1-cyclobutyl-4-(4-morpholinylcarbonyl)-1H-pyrazol-5-yl]-13-cyclohexyl-3-methoxy-N-[(2-methylpropyl)sulfonyl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide