tert-butyl 13-cyclohexyl-6-((2E,Z)-3-(dimethylamino)-2-(ethoxycarbonyl)-2-propenoyl)-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylate | 1127234-89-2

分子结构分类

有机化合物 - 有机杂环化合物 - 吲哚及其衍生物

中文名称

——

中文别名

——

英文名称

tert-butyl 13-cyclohexyl-6-((2E,Z)-3-(dimethylamino)-2-(ethoxycarbonyl)-2-propenoyl)-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylate

英文别名

tert-butyl 13-cyclohexyl-6-[3-(dimethylamino)-2-ethoxycarbonylprop-2-enoyl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylate

tert-butyl 13-cyclohexyl-6-((2E,Z)-3-(dimethylamino)-2-(ethoxycarbonyl)-2-propenoyl)-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylate化学式

CAS

1127234-89-2

化学式

C₃₇H₄₄N₂O₆

mdl

——

分子量

612.766

InChiKey

ZJLJIMHWQRHBQM-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

7.7
重原子数：

45
可旋转键数：

11
环数：

5.0
sp3杂化的碳原子比例：

0.43
拓扑面积：

87.1
氢给体数：

0
氢受体数：

7

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	13-cyclohexyl-10-[(1,1-dimethylethoxy)carbonyl]-3-methoxy-beta-oxo-7H-indolo[2,1-a][2]benzazepine-6-propanoic acid ethyl ester	1127234-87-0	C₃₄H₃₉NO₆	557.687

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	13-cyclohexyl-6-((2E,Z)-3-(dimethylamino)-2-(ethoxycarbonyl)-2-propenoyl)-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid	1127238-03-2	C₃₃H₃₆N₂O₆	556.659
——	13-cyclohexyl-6-[4-(ethoxycarbonyl)-1-methyl-1H-pyrazol-3-yl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid 1,1-dimethylethyl ester	1127234-92-7	C₃₆H₄₁N₃O₅	595.739
——	13-cyclohexyl-6-[4-(ethoxycarbonyl)-1-methyl-1H-pyrazol-5-yl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid 1,1-dimethylethyl ester	1127234-91-6	C₃₆H₄₁N₃O₅	595.739
——	13-cyclohexyl-6-[1-cyclopropyl-4-(ethoxycarbonyl)-1H-pyrazol-3-yl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid 1,1-dimethylethyl ester	1195781-75-9	C₃₈H₄₃N₃O₅	621.777
——	13-cyclohexyl-6-[4-(ethoxycarbonyl)-1-ethyl-1H-pyrazol-5-yl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid 1,1-dimethylethyl ester	1127236-29-6	C₃₇H₄₃N₃O₅	609.766
——	13-cyclohexyl-6-[4-(ethoxycarbonyl)-1-(1-methylethyl)-1H-pyrazol-5-yl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid 1,1-dimethylethyl ester	1127236-32-1	C₃₈H₄₅N₃O₅	623.792
——	13-cyclohexyl-6-[4-(ethoxycarbonyl)-1-(1-methyl-4-piperidinyl)-1H-pyrazol-5-yl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid 1,1-dimethylethyl ester	1195781-03-3	C₄₁H₅₀N₄O₅	678.872
——	6-[1-cyclobutyl-4-(ethoxycarbonyl)-1H-pyrazol-5-yl]-13-cyclohexyl-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid 1,1-dimethylethyl ester	1195778-70-1	C₃₉H₄₅N₃O₅	635.803
——	13-cyclohexyl-6-[1-cyclopropyl-4-(ethoxycarbonyl)-1H-pyrazol-3-yl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid	1195781-83-9	C₃₄H₃₅N₃O₅	565.669
——	13-cyclohexyl-6-[4-(ethoxycarbonyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-5-yl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid 1,1-dimethylethyl ester	1195778-31-4	C₄₀H₄₇N₃O₆	665.83
——	13-cyclohexyl-6-[4-(ethoxycarbonyl)-1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl]-3-methoxy-7H-indolo[2,1-a] [2]benzazepine-10-carboxylic acid 1,1-dimethylethyl ester	1127236-92-3	C₃₇H₄₀F₃N₃O₅	663.737
——	13-cyclohexyl-6-[1-cyclopropyl-4-(ethoxycarbonyl)-1H-pyrazol-5-yl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid	1195781-78-2	C₃₄H₃₅N₃O₅	565.669
——	6-[1-cyclobutyl-4-(ethoxycarbonyl)-1H-pyrazol-5-yl]-13-cyclohexyl-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid	1195781-72-6	C₃₅H₃₇N₃O₅	579.696
——	13-cyclohexyl-6-[4-(ethoxycarbonyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-5-yl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid	1195778-33-6	C₃₆H₃₉N₃O₆	609.722
——	13-cyclohexyl-6-[1-cyclopropyl-4-(4-morpholinylcarbonyl)-1H-pyrazol-3-yl]-3-methoxy-N-[(1-methylethyl)sulfonyl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide	1195779-44-2	C₃₉H₄₅N₅O₆S	711.882
——	13-cyclohexyl-6-[4-(ethoxycarbonyl)-1-(3-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid 1,1-dimethylethyl ester	1195778-00-7	C₄₁H₄₄N₄O₅	672.824
——	1-cyclobutyl-5-[13-cyclohexyl-3-methoxy-10-[[[(1-methylethyl)sulfonyl]amino]carbonyl]-7H-indolo[2,1-a][2]benzazepin-6-yl]-1H-pyrazole-4-carboxylic acid ethyl ester	1195780-98-3	C₃₈H₄₄N₄O₆S	684.857
——	1-cyclobutyl-5-[13-cyclohexyl-3-methoxy-10-[[[(2-methylpropyl)sulfonyl]amino]carbonyl]-7H-indolo[2,1-a][2]benzazepin-6-yl]-1H-pyrazole-4-carboxylic acid ethyl ester	1195778-72-3	C₃₉H₄₆N₄O₆S	698.883
——	5-[13-cyclohexyl-3-methoxy-10-[[[(1-methylethyl)sulfonyl]amino]carbonyl]-7H-indolo[2,1-a][2]benzazepin-6-yl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxylic acid ethyl ester	1195781-10-2	C₃₉H₄₆N₄O₇S	714.883
——	5-[13-cyclohexyl-3-methoxy-10-[[[(2-methylpropyl)sulfonyl]amino]carbonyl]-7H-indolo[2,1-a][2]benzazepin-6-yl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxylic acid ethyl ester	1195778-35-8	C₄₀H₄₈N₄O₇S	728.91
——	1-cyclobutyl-5-[13-cyclohexyl-3-methoxy-10-[[[(1-methylethyl)sulfonyl]amino]carbonyl]-7H-indolo[2,1-a][2]benzazepin-6-yl]-1H-pyrazole-4-carboxylic acid	1195778-76-7	C₃₆H₄₀N₄O₆S	656.803
——	13-cyclohexyl-6-[1-cyclopropyl-4-(4-morpholinylcarbonyl)-1H-pyrazol-5-yl]-3-methoxy-N-[(1-methylethyl)sulfonyl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide	1127238-75-8	C₃₉H₄₅N₅O₆S	711.882
——	1-cyclobutyl-5-[13-cyclohexyl-3-methoxy-10-[[[(2-methylpropyl)sulfonyl]amino]carbonyl]-7H-indolo[2,1-a][2]benzazepin-6-yl]-1H-pyrazole-4-carboxylic acid	1195778-74-5	C₃₇H₄₂N₄O₆S	670.83
——	5-[13-cyclohexyl-3-methoxy-10-[[[(1-methylethyl)sulfonyl]amino]carbonyl]-7H-indolo[2,1-a][2]benzazepin-6-yl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxylic acid	1195781-12-4	C₃₇H₄₂N₄O₇S	686.829
——	6-[1-cyclobutyl-4-(1-cyclopentylpiperazin-4-ylcarbonyl)-1H-pyrazol-5-yl]-13-cyclohexyl-3-methoxy-N-[(1-methylethyl)sulfonyl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide	1195780-11-0	C₄₅H₅₆N₆O₅S	793.043
——	5-[13-cyclohexyl-3-methoxy-10-[[[(2-methylpropyl)sulfonyl]amino]carbonyl]-7H-indolo[2,1-a][2]benzazepin-6-yl]-1'-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxylic acid	1195778-37-0	C₃₈H₄₄N₄O₇S	700.856