Sulfide, bis(2-hydroxybutyl) | 875855-27-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Sulfide, bis(2-hydroxybutyl)
• 英文别名: 1-(2-hydroxybutylsulfanyl)butan-2-ol
• CAS: 875855-27-9
• 化学式: C₈H₁₈O₂S
• 分子量: 178.296
• InChiKey: VKVGWFUYIKJFSB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  65.8
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-(4-chlorobenzyl)-4-hydroxy-6-(4-morpholinylmethyl)-3-quinolinecarboxamide 、 三苯基膦 、 Sulfide, bis(2-hydroxybutyl) 、 偶氮二甲酸二乙酯 在 氩 、 crude product 、 甲醇 、 二氯甲烷 作用下， 以 四氢呋喃 为溶剂， 反应 16.0h， 以to afford 0.21 gm of the title compound as a white solid的产率得到N-(4-chlorobenzyl)-1-[2-(ethylsulfanyl)ethyl]-6-(4-morpholinylmethyl)-4-oxo-1,4-dihydro-3-quinolinecarboxamide
  参考文献：
  名称：

  Quinolinecarboxamides as antiviral agents

  摘要：

  本发明提供了一种I式化合物，其作为抗病毒剂特别是作为针对疱疹病毒家族的药剂使用。

  公开号：

  US06248739B1
• 作为产物：
  描述：

  1,2-环氧丁烷 在 sodium sulfide 、 水 作用下， 生成 Sulfide, bis(2-hydroxybutyl)
  参考文献：
  名称：

  Simple and highly efficient catalyst- and waste-free ring opening of epoxides with Na2S in water

  摘要：

  Water was found to be a highly efficient and green catalyst and solvent for ring-opening reaction of epoxides with Na2S at room temperature to give substituted bis(hydroxyethyl)thioethers in high yields.

  DOI：

  10.1007/s00706-010-0261-0

文献信息

• NOVEL SELECTIVE HYDROGENATION CATALYST COMPRISING PALLADIUM ON POROUS SILICA GLASS AND THE USE THEREOF
  申请人：Bonrath Werner

  公开号：US20110237841A1

  公开（公告）日：2011-09-29

  The present invention is directed to a catalyst comprising palladium on a porous Silica glass as carrier, as well as to the use of such catalyst for the selective hydrogenation of alkines to alkenes.

  本发明涉及一种催化剂，其载体为多孔硅玻璃上的钯，以及将该催化剂用于选择性氢化烯烃为烯烃的方法。
• Improvements in or relating to siloxanes
  申请人：M & T CHEMICALS, INC.

  公开号：EP0054426A2

  公开（公告）日：1982-06-23

  The properties of polymeric compositions can be improved by the presence of a polysiloxane unit of formula where Q is a substituted or unsubstituted aromatic group, D is unsubstituted or substituted hydrocarbylene R1, R2, R3, R4, R5 and R6 each, independently, is unsubstituted or substituted hydrocarbyl. x, y and z each independently has a value from 0 to 100. Polyimides containing these units display improved solubility and adhesion; they are useful, among other things, as protective coatings.

  聚合体组合物的性能可以通过存在式中的聚硅氧烷单元得到改善 式中 Q 是取代或未取代的芳香基团、 D为未取代或取代的烃基 R1、R2、R3、R4、R5 和 R6 各自独立地为未取代或取代的烃基。 x、y 和 z 各自独立地具有 0 至 100 之间的数值。 含有这些单元的聚酰亚胺具有更好的溶解性和粘附性，可用作保护涂层等。
• Siloxane crosslinking processes employing sulfur compounds and platinum catalysts
  申请人：Momentive Performance Materials Inc.

  公开号：US10457795B2

  公开（公告）日：2019-10-29

  Provided is a composition and process for producing a crosslinked product. The composition comprises a mixture constituting (a) an alkenyl silicone, (b) a hydrogen siloxane, (c) a cure inhibitor and (d) a hydrosilylation catalyst, optionally in the presence of a solvent, and (e) sulfur compounds in order to produce the crosslinked product, and the process comprises reacting such a composition to form a crosslinked product.

  本文提供了一种生产交联产品的组合物和工艺。该组合物包括由(a)烯基硅氧烷、(b)氢硅氧烷、(c)固化抑制剂和(d)氢化硅催化剂（可选择在有溶剂存在的情况下）以及(e)硫化合物组成的混合物，以生产交联产品，该工艺包括使该组合物反应以形成交联产品。
• Lubricant composition
  申请人：Dow Global Technologies LLC

  公开号：US10752860B2

  公开（公告）日：2020-08-25

  An antioxidant package composition including a combination of: (i) at least one aromatic amine, and (ii) at least one polyether sulphide; a lubricant composition including: (a) the above antioxidant package and (b) at least one base oil; a process for preparing the antioxidant package; and a process for preparing the lubricant composition.

  一种抗氧化剂包组合物，包括以下物质的组合 (i) 至少一种芳香胺和 (ii) 至少一种聚醚硫化物；一种润滑剂组合物，包括：(a) 上述抗氧化剂包和 (b) 至少一种基础油；一种制备抗氧化剂包的工艺；以及一种制备润滑剂组合物的工艺。
• Biocompatible metallic materials grafted with biologically active compounds and preparation thereof
  申请人：——

  公开号：US20010037144A1

  公开（公告）日：2001-11-01

  Disclosed are surface-modified medical metallic materials and preparation thereof. The medical metallic material is prepared by coating a gold or silver thin layer onto a base metal, adsorbing a polyfunctional sulfur compound onto the gold or silver thin layer, and chemically bonding a biologically active material such as heparin or estradiol to the functional group of the sulfur compound. The biologically active material is firmly bonded to the base metal via the sulfur compound. Being significantly improved in antithrombogenicity and biocompatibility, the metallic materials are suitable for use in various implants, including stents, artificial cardiac valves and catheters.

  本发明公开了表面改性的医用金属材料及其制备方法。这种医用金属材料的制备方法是：在基底金属上涂覆一层金或银薄层，在金或银薄层上吸附一种多官能团硫化合物，然后将肝素或雌二醇等生物活性材料化学键合到硫化合物的官能团上。生物活性材料通过硫化合物与基底金属牢固地结合在一起。这种金属材料的抗血栓形成性和生物相容性得到明显改善，适用于各种植入物，包括支架、人工心脏瓣膜和导管。